公开(公告)号：EP0036927A2

公开(公告)日：1981-10-07

申请号：EP81100688.1

申请日：1981-01-30

申请人： Gambro Lundia AB ,  Gambro AG

发明人： Riede, Gerhard ,  Nilsson, Nils-Joel Eddie

IPC分类号： B01D13/00 ,  A61M1/03

CPC分类号： B01D53/22 ,  B01D61/28 ,  B01D63/084 ,  B01D2313/14

摘要： A device for the diffusion of substances between two fluids via semipermeable membranes (2) which are arranged in a stack separated by spacer plates (1) which comprise through-holes (13, 23) connected to inlets and outlets respectively for the respective fluids, a first fluid of which is arranged so as to be conducted on one side of the respective membranes and a second fluid on the opposite side of the same membranes. Preferably the membranes (2) are arranged in pairs between the spacer plates (1). The inlet and/or the outlet (18), for at least one of the said fluids, is connected from the side to a duct (12) intersecting the stack and formed by the said through-holes (13).
The device is intended and foremost to be used as a so-called artificial kidney, the said fluids consisting of blood and dialysis liquid respectively.

摘要翻译： 一种用于通过半透膜（2）在两个流体之间扩散物质的装置，该膜通过间隔板（1）分开堆叠而成，该堆叠包括分别连接到各流体的入口和出口的通孔（13,23） 其第一流体布置成在各个膜的一侧上进行传导，而在相同的膜的相对侧上布置第二流体。 优选地，膜（2）成对地布置在间隔板（1）之间。 用于至少一种所述流体的入口和/或出口（18）从侧面连接到与堆叠相交并由所述通孔（13）形成的管道（12）。 该装置主要用作所谓的人造肾，所述液体分别由血液和透析液组成。

公开(公告)号：EP0091571B1

公开(公告)日：1988-07-13

申请号：EP83102690.1

申请日：1981-01-30

申请人： Gambro Lundia AB ,  Gambro AG

发明人： Riede, Gerhard ,  Nilsson, Nils-Joel Eddie

IPC分类号： B01D13/00 ,  A61M1/16

CPC分类号： B01D53/22 ,  B01D61/28 ,  B01D63/084 ,  B01D2313/14

公开(公告)号：EP0036927A3

公开(公告)日：1981-10-28

申请号：EP81100688

申请日：1981-01-30

申请人： Gambro Lundia AB ,  Gambro AG

发明人： Riede, Gerhard ,  Nilsson, Nils-Joel Eddie

IPC分类号： B01D13/00 ,  A61M01/03 ,  B01D53/22

CPC分类号： B01D53/22 ,  B01D61/28 ,  B01D63/084 ,  B01D2313/14

摘要： A device for the diffusion of substances between two fluids via semipermeable membranes (2) which are arranged in a stack separated by spacer plates (1) which comprise through-holes (13, 23) connected to inlets and outlets respectively for the respective fluids, a first fluid of which is arranged so as to be conducted on one side of the respective membranes and a second fluid on the opposite side of the same membranes. Preferably the membranes (2) are arranged in pairs between the spacer plates (1). The inlet and/or the outlet (18), for at least one of the said fluids, is connected from the side to a duct (12) intersecting the stack and formed by the said through-holes (13). The device is intended and foremost to be used as a so-called artificial kidney, the said fluids consisting of blood and dialysis liquid respectively.

摘要翻译： 一种用于通过半透膜（2）在两个流体之间扩散物质的装置，该膜通过间隔板（1）分开堆叠而成，该堆叠包括分别连接到各流体的入口和出口的通孔（13,23） 其第一流体布置成在各个膜的一侧上进行传导，而在相同的膜的相对侧上布置第二流体。 优选地，膜（2）成对地布置在间隔板（1）之间。 用于至少一种所述流体的入口和/或出口（18）从侧面连接到与堆叠相交并由所述通孔（13）形成的管道（12）。 该装置主要用作所谓的人造肾，所述液体分别由血液和透析液组成。

公开(公告)号：EP0091571A3

公开(公告)日：1986-09-10

申请号：EP83102690

申请日：1981-01-30

申请人： Gambro Lundia AB ,  Gambro AG

发明人： Riede, Gerhard ,  Nilsson, Nils-Joel Eddie

IPC分类号： B01D13/00 ,  A61M01/03

CPC分类号： B01D53/22 ,  B01D61/28 ,  B01D63/084 ,  B01D2313/14

摘要： A device for the diffusion of substances between two fluids via semipermeable membranes (2) which are arranged in a stack separated by spacer plates (1), which comprise through-holes (13, 23) connected to inlets and outlets respectively for the respective fluids, a first fluid of which is arranged so as to be conducted on one side of the respective membranes and a second fluid on the opposite side of the same membranes. Preferably the membranes (2) are arranged in pairs between the spacer plates (1). The inlet and/or the outlet (18), for at least one of the said fluids, is connected from the side to a duct (12) intersecting the stack and formed by the said through-holes (13). The device is intended first and foremost to be used as a so-called artificial kidney, the said fluids consisting of blood and dialysis liquid respectively.

摘要翻译： 一种用于通过半透膜（2）在两种流体之间扩散物质的装置，所述半透膜（2）布置在由间隔板（1）隔开的堆叠中，所述间隔板包括连接到相应流体的入口和出口的通孔（13,23） 其第一流体布置成在相应膜的一侧上传导并且在相同膜的相对侧上传导第二流体。 优选地，膜（2）成对地布置在隔板（1）之间。 至少一个所述流体的入口和/或出口（18）从一侧连接到与堆叠相交并由所述通孔（13）形成的管道（12）。 该装置首先被用作所谓的人造肾，所述流体分别由血液和透析液组成。

公开(公告)号：EP0091571A2

公开(公告)日：1983-10-19

申请号：EP83102690.1

申请日：1981-01-30

申请人： Gambro Lundia AB ,  Gambro AG

发明人： Riede, Gerhard ,  Nilsson, Nils-Joel Eddie

IPC分类号： B01D13/00 ,  A61M1/16

CPC分类号： B01D53/22 ,  B01D61/28 ,  B01D63/084 ,  B01D2313/14

摘要： A device for the diffusion of substances between two fluids via semipermeable membranes (2) which are arranged in a stack separated by spacer plates (1), which comprise through-holes (13, 23) connected to inlets and outlets respectively for the respective fluids, a first fluid of which is arranged so as to be conducted on one side of the respective membranes and a second fluid on the opposite side of the same membranes. Preferably the membranes (2) are arranged in pairs between the spacer plates (1). The inlet and/or the outlet (18), for at least one of the said fluids, is connected from the side to a duct (12) intersecting the stack and formed by the said through-holes (13).
The device is intended first and foremost to be used as a so-called artificial kidney, the said fluids consisting of blood and dialysis liquid respectively.

摘要翻译： 一种用于通过半透膜（2）在两个流体之间扩散物质的装置，该膜通过间隔板（1）分开堆叠而成，该堆叠包括分别连接到相应流体的入口和出口的通孔（13,25） 其第一流体布置成在相应的膜的一侧上被传导，并且在相同膜的相对侧上的第二流体，优选地，膜（2）成对地布置在间隔板（1）之间， 。 用于至少一种所述流体的入口和/或出口（18）从侧面连接到与堆叠相交并由所述通孔（13）形成的管道（12）。 该装置首先和首要用作所谓的人造肾，所述流体分别由血液和透析液组成。

公开(公告)号：EP0324922B1

公开(公告)日：1992-08-12

申请号：EP88119648.9

申请日：1988-11-25

申请人： Gambro AG

发明人： Flank, Hans Peder ,  Nilsson, Nils-Joel Eddie ,  Riede, Gerhard

IPC分类号： B01D63/08

CPC分类号： B01D63/084 ,  B01D63/082

公开(公告)号：EP0324922A2

公开(公告)日：1989-07-26

申请号：EP88119648.9

申请日：1988-11-25

申请人： Gambro AG

发明人： Flank, Hans Peder ,  Nilsson, Nils-Joel Eddie ,  Riede, Gerhard

IPC分类号： B01D63/08

CPC分类号： B01D63/084 ,  B01D63/082

摘要： Semipermeable membranes (2) are arranged in a stack separated by supporting plates (1) having a first plane face and a second plane face (10,12) and comprising through-openings (7,8) connected to an inlet and outlet, respectively, for a first fluid, by means of which this first fluid is conducted to the one side of the respective membrane, whilst a second fluid is conducted ot the other side of the membrane, the stack of membranes and supporting plates having an elongated shape with a flow-through duct formed of the said through-openings (7,8) arranged straight through the stack near its two ends.
The invention is characterized by channels (11,11′) originating from end edges (9,9′) of the supporting plates, open towards a frist plane face (10,12), for the conducting of the said second fluid past a seal (13,13a′) arranged on the opposite plane face (12,10) to an opening (14,14′) passing through the plate for the conducting of this second fluid to, respectively from, the space inside the said seal (13,13a′) on the said opposite plane face (12,10) of the plate.
The arrangement in accordance with the invention is intended in particular to be used in connection with dialysis, haemofiltration and similar extracorporeal procedures for the treatment of blood.

摘要翻译： 半透膜（2）布置成由具有第一平面和第二平面（10,12）的支撑板（1）隔开的堆叠中，并且包括分别连接到入口和出口的通孔（7,8） 对于第一流体，通过该第一流体将第一流体传导到相应膜的一侧，而第二流体在膜的另一侧被传导，膜和支撑板的堆叠具有细长形状， 由所述通孔（7,8）形成的流通管道，其直接穿过堆叠在其两端附近布置。 本发明的特征在于源自支撑板的端边缘（9,9分钟）的通道（11,11分钟），朝向第一平面（10,12）打开，用于将所述第二流体通过密封件 （13,13a min）设置在相对的平面（12,10）上的通向板的开口（14,14分钟），用于将该第二流体分别从所述密封件（13）内的空间 ，13a）在板的所述相对的平面（12,10）上。 根据本发明的装置特别用于结合透析，血液滤过和用于治疗血液的类似的体外方法。

公开(公告)号：EP0324922A3

公开(公告)日：1989-12-13

申请号：EP88119648.9

申请日：1988-11-25

申请人： Gambro AG

发明人： Flank, Hans Peder ,  Nilsson, Nils-Joel Eddie ,  Riede, Gerhard

IPC分类号： B01D63/08

CPC分类号： B01D63/084 ,  B01D63/082

摘要： Semipermeable membranes (2) are arranged in a stack separated by supporting plates (1) having a first plane face and a second plane face (10,12) and comprising through-openings (7,8) connected to an inlet and outlet, respectively, for a first fluid, by means of which this first fluid is conducted to the one side of the respective membrane, whilst a second fluid is conducted ot the other side of the membrane, the stack of membranes and supporting plates having an elongated shape with a flow-through duct formed of the said through-openings (7,8) arranged straight through the stack near its two ends. The invention is characterized by channels (11,11′) originating from end edges (9,9′) of the supporting plates, open towards a frist plane face (10,12), for the conducting of the said second fluid past a seal (13,13a′) arranged on the opposite plane face (12,10) to an opening (14,14′) passing through the plate for the conducting of this second fluid to, respectively from, the space inside the said seal (13,13a′) on the said opposite plane face (12,10) of the plate. The arrangement in accordance with the invention is intended in particular to be used in connection with dialysis, haemofiltration and similar extracorporeal procedures for the treatment of blood.