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公开(公告)号:EP3999073A1
公开(公告)日:2022-05-25
申请号:EP20840846.8
申请日:2020-07-17
发明人: LAUDER, Scott , PURCELL, Tom , GOVINDARAJAN, Sridhar , KUIJPERS, Taco Willem , WOUTERS, Diana , BROUWER, Maria Clara , POUW, Richard Benjamin , RISPENS, Taede , JONGERIUS, Ilse , DEKKERS, Gillian
IPC分类号: A61K31/7088 , A61K35/76 , A61K38/00 , A61K39/395 , C07K16/18 , C07K16/36
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公开(公告)号:EP3183266B1
公开(公告)日:2019-05-29
申请号:EP15787045.2
申请日:2015-08-20
IPC分类号: C07K16/18 , C12N15/13 , A61K39/395
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公开(公告)号:EP3183266A1
公开(公告)日:2017-06-28
申请号:EP15787045.2
申请日:2015-08-20
IPC分类号: C07K16/18 , C12N15/13 , A61K39/395
CPC分类号: C07K16/18 , A61K39/3955 , C07K16/36 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/76
摘要: The invention relates to isolated, synthetic or recombinant antibodies and fragments thereof specific for factor H. The invention further relates to the use of such antibodies and fragments for inhibiting complement activation and treatment of disorders associated with complement activation.
摘要翻译: 本发明涉及对因子H特异的分离的,合成的或重组的抗体及其片段。本发明进一步涉及这种抗体和片段用于抑制补体激活和治疗与补体活化有关的病症的用途。
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