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19 条记录 (耗时 0.013 秒)

    METHODS AND DEVICES FOR CALIBRATING AND/OR MONITORING OPTICAL MEASUREMENT DEVICES
    2.
    发明公开
    METHODS AND DEVICES FOR CALIBRATING AND/OR MONITORING OPTICAL MEASUREMENT DEVICES 审中-公开
    用于校准和/或监测光学测量装置的方法和设备

    公开(公告)号：EP3308141A1

    公开(公告)日：2018-04-18

    申请号：EP16730200.9

    申请日：2016-06-08

    申请人： Gen-Probe Incorporated

    发明人： HAGEN, Norbert D. ,  OPALSKY, David ,  WALKER, George T. ,  KNIGHT, Byron J.

    IPC分类号： G01N21/27 ,  G01N21/64

    CPC分类号： G01N21/64 ,  G01N21/276 ,  G01N21/645

    摘要： An optical signal detection module includes an optical measurement device (OMD) configured to detect an optical emission signal from an emission signal source placed in a signal-detecting position of the OMD. The optical signal detection module also includes a cover moveable between a closed position covering the signal-detecting position and an open position not covering the signal-detecting position. The cover includes an optical reference material that emits a reference emission detectable by the OMD. The cover is configured so that, when the cover is in the closed position, the inner surface is in the signal-detecting position of the OMD so that the OMD detects the reference emission. The optical signal detection module can also include a drive assembly coupled to the cover and configured to move the cover between the open position and the closed position. In some embodiments, the OMD can include a fluorometer.

    METHOD AND APPARATUS FOR EFFECTING AUTOMATED MOVEMENT OF A MAGNET IN AN INSTRUMENT FOR PERFORMING A MAGNETIC SEPARATION PROCEDURE
    3.
    发明公开
    METHOD AND APPARATUS FOR EFFECTING AUTOMATED MOVEMENT OF A MAGNET IN AN INSTRUMENT FOR PERFORMING A MAGNETIC SEPARATION PROCEDURE 审中-公开
    方法和设备的自动生效移动磁铁的仪器用于实现磁选工艺

    公开(公告)号：EP2429710A1

    公开(公告)日：2012-03-21

    申请号：EP10719719.6

    申请日：2010-05-17

    申请人： Gen-Probe Incorporated

    发明人： DAVIS, Christopher Brandon ,  HAGEN, Norbert D. ,  KNIGHT, Byron J. ,  OPALSKY, David ,  TUGGLE, James T.

    IPC分类号： B03C1/28 ,  B03C1/033

    摘要： Methods, systems, and apparatus are provided for automated isolation of selected analytes, to which magnetically-responsive solid supports are bound, from other components of a sample. An apparatus for performing an automated magnetic separation procedure includes a mechanism for effecting linear movement of a magnet between operative and non-operative positions with respect to a receptacle device. A receptacle holding station within which a receptacle device may be temporarily stored prior to moving the receptacle to the apparatus for performing magnetic separation includes magnets for applying a magnetic field to the receptacle device held therein, thereby drawing at least a proton of the magnetically-responsive solid supports out of suspension before the receptacle device is moved to the magnetic separation station. An automated receptacle transport mechanism moves the receptacle devices between the apparatus for performing magnetic separation and the receptacle holding station.

    A RECEPTACLE FOR RECEIVING ONE OR MORE SUBSTANCES TO BE LYOPHILIZED
    4.
    发明公开
    A RECEPTACLE FOR RECEIVING ONE OR MORE SUBSTANCES TO BE LYOPHILIZED 审中-公开

    公开(公告)号：EP3949732A1

    公开(公告)日：2022-02-09

    申请号：EP21196662.7

    申请日：2016-08-02

    申请人： Gen-Probe Incorporated

    发明人： KNIGHT, Byron J.

    IPC分类号： A01N1/02 ,  B01L7/00 ,  B01L9/06 ,  F26B5/06 ,  F26B25/06

    摘要： There is disclosed a receptacle (200) for receiving one or more substances to be lyophilized, the receptacle comprising: one or more wells (201), each well configured to hold a substance to be lyophilized and comprising an at least substantially hemispherical shaped bottom interior surface; and a sealable upper surface (202) configured such that a seal (203) may be applied thereto and sealed such that each of the one or more wells are individually sealed and isolated from an uncontrolled environment external to the sealed receptacle, wherein an exterior shape of at least a bottom portion of the receptacle is configured to conform with a receptacle receiving portion (16) of a lyophilization nest (1), so as to maximize a surface contact area between the receptacle and the corresponding receptacle receiving portion, and wherein the receptacle comprises a low vapor transmission rate material configured to impede migration of water vapor through the material.

    CONTAMINATION CONTROL FOR LIQUID HANDLING
    5.
    发明公开
    CONTAMINATION CONTROL FOR LIQUID HANDLING 有权
    KONTROLLE DER KONTAMINATION BEI DER HANDHABUNG VONFLÜSSIGKEITEN

    公开(公告)号：EP2429709A2

    公开(公告)日：2012-03-21

    申请号：EP10733062.3

    申请日：2010-05-17

    申请人： Gen-Probe Incorporated ,  Rhubottom, Jason F. ,  Stratec Biomedical AG

    发明人： RHUBOTTOM, Jason F. ,  CLARK, Craig B. ,  GILKER, John M. ,  HAGEN, Norbert D. ,  HORN, Tom R. ,  KNIGHT, Byron J. ,  OPALSKY, David ,  LUKHAUB, Waldemar ,  HÖRGER, Olaf

    IPC分类号： B01L9/06

    CPC分类号： G06Q10/087 ,  B01L9/06 ,  B01L2200/023 ,  B01L2200/06 ,  B01L2200/141 ,  B01L2300/021 ,  G01N35/1004

    摘要： A structure for holding sample-containing receptacles includes a cover with holes formed therein through which the receptacles can be accessed with a substance transfer mechanism, such as a robotic pipettor. When the transfer mechanism is inserted into and then withdrawn from a receptacle, a string of viscous material may be suspended from the mechanism. A viscous string removal element adjacent each opening engages the string of viscous material and dislodges the string from the mechanism when the mechanism moves in a prescribed path with respect to the removal element. A sample rack configured to hold receptacles and to be inserted into the structure below the cover includes a sample rack having receptacle-receiving pockets, each with a resilient element and a positioning feature for holding receptacles of varying sizes in a predetermined position within the receptacle receiving pocket, and a cover including features for preventing a receptacle from being pulled out of its receptacle-receiving pocket when the transfer mechanism is withdrawn from the receptacle.

    摘要翻译： 用于保持含有样品的容器的结构包括其中形成有孔的盖，通过该盖可以用诸如机器人移液器的物质转移机构接近容器。 当传送机构插入到容器中然后从容器中取出时，一串粘性材料可以悬挂在机构上。 邻近每个开口的粘性排除元件与粘性材料串接合，并且当机构相对于去除元件以规定的路径移动时，将串从机构中移出。 配置成保持插座并插入到盖下方的结构中的样品架包括具有插座容纳凹部的样品架，每个具有弹性元件和用于在插座接收中的预定位置保持不同尺寸的容器的定位特征 口袋和盖子，其包括当传送机构从容器中取出时用于防止插座从其插座接收袋中被拉出的特征。

    SYSTEM, METHOD, AND APPARATUS FOR AUTOMATED INCUBATION
    8.
    发明公开
    SYSTEM, METHOD, AND APPARATUS FOR AUTOMATED INCUBATION 审中-实审

    公开(公告)号：EP4309790A3

    公开(公告)日：2024-03-27

    申请号：EP23214994.8

    申请日：2013-07-31

    申请人： Gen-Probe Incorporated

    发明人： BUSE, David ,  COMBS, David ,  HAGEN, Norbert ,  OPALSKY, David ,  RICHARDSON, Bruce ,  PRASAD, Anita ,  MORAVICK, Keith ,  MOORE, Tyler ,  KNIGHT, Byron J.

    IPC分类号： B65H1/00 ,  C12Q1/68 ,  B01L3/00

    摘要： There is disclosed an apparatus comprising: a receptacle holder comprised of a heat-conducting material and including a plurality of receptacle wells, wherein each receptacle well is configured to receive a receptacle therein and includes a through-hole extending from an inner surface of the receptacle well to an outer surface of the receptacle holder; a plurality of optical fibers, each optical fiber having first and second ends, wherein the first end is in optical communication with one of the receptacle wells, and the second end is in optical communication with at least one of an excitation signal source and an emission signal detector, wherein the first end of each optical fiber is disposed outside or within, or extends through, a corresponding through-hole in each receptacle well, and wherein the first end of each optical fiber is moveable within the corresponding through-hole relative to the surface of the receptacle well; one or more thermal elements positioned proximal to the receptacle holder for altering a temperature or temperatures of the receptacle holder, wherein the thermal element is positioned proximal to a side surface of the receptacle holder, and provides thermal energy through the receptacle holder to each of the plurality of receptacle wells; one or more support(s), each positioned proximal to the side surface of the receptacle holder, wherein the one or more thermal elements are positioned between the support and the receptacle holder, and wherein the support comprises a heat sink, or the support is provided in thermal communication with a heat sink; and one or more thermal devices disposed within the heat sink for pre-heating the heat sink.