公开(公告)号：EP2413976A1

公开(公告)日：2012-02-08

申请号：EP10710834.2

申请日：2010-03-19

申请人： General Electric Company

发明人： CARTER, Randall, Lee ,  CASTLE, Jason, William ,  FISH, Kenneth, Michael ,  SOOD, Anup ,  STAPLES, Natalie, Anne ,  LEE, Brian Duh-lan

IPC分类号： A61K49/00

CPC分类号： A61K49/0032 ,  A61K49/0054

摘要： The present invention relates to a method of in vivo optical imaging, of the margins around tumours, which comprises an optical imaging contrast agent. The optical imaging agents comprise conjugates of near-infrared dyes with synthetic polyethyleneglycol (PEG) polymers having a molecular weight in the range 15-45 kDa. Also disclosed are optical imaging contrast agents, pharmaceutical compositions and kits.