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1.发明公开
公开(公告)号：EP4403621A1
公开(公告)日：2024-07-24
申请号：EP23152532.0
申请日：2023-01-19
发明人： Betz, Timo , Münker, Till , Hofemeier, Arne
CPC分类号： C12M35/04 , C12M21/08 , C12M23/12 , C12M23/22 , C12M23/38 , C12M31/02 , C12M31/08 , C12M35/02 , C12M41/46
摘要： A device (1) for cultivating tissue (28) and observing contractions of the tissue (28) comprises a lower component (2), the lower component (2) defining a culture chamber (5) having a transparent bottom, a side wall and an open top, and an upper component (6) fitting on the lower component (2) and having a base plate (7) and two elastic posts (9). Each of the two elastic posts (9) extends downwards from the base plate (7) and has an upper post end (11) that is fixed to the base plate (7) and a free lower post end (10). The two elastic posts (9) are arranged at a lateral post distance (16). When the upper component (6) is fitted on the lower component (2), the two elastic posts (9) extend into the culture chamber (5), the two elastic posts (9) being arranged at lateral wall distances to the sidewall and their lower post ends (10) facing the bottom of the culture chamber (5). Each of the two elastic posts (9) includes a light guide (12) configured and arranged for coupling-in light (29) at the respective upper post end (11) and for coupling-out the light (29) at the respective lower post end (10) and through the bottom of the culture chamber (5). A piezoelectric bending transducer (13) extends downwards from the base plate (7) and has an upper transducer end (14) that is fixed to the base plate (7) and a lower transducer end (15) that is attached to one of the two elastic posts (9) at a vertical distance to its lower post end (10).
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