公开(公告)号：EP4098313A1

公开(公告)日：2022-12-07

申请号：EP22186878.9

申请日：2014-09-30

申请人： Georgia Tech Research Corporation

发明人： MCALLISTER, Devin ,  PRAUSNITZ, Mark ,  HENRY, Sebastian ,  NORMAN, James J.

IPC分类号： A61M37/00

摘要： A microneedle patch for administration of a substance of interest into a biological tissue, the microneedle patch comprising: a base substrate having a microneedle side and an opposing back side; solid microneedles extending from the microneedle side of the base substrate, the solid microneedles being formed of a composition which comprises (i) a substance of interest selected from active pharmaceutical ingredients, allergens, vitamins, cosmetic agents, cosmeceuticals, and markers, and (ii) a matrix material in which the substance of interest is dispersed; and an indicator connected to the opposing back side of the base substrate, wherein the indicator is configured to provide an audible, tactile, and visual signal when a force applied to the patch by a user, in the course of applying the patch to a biological tissue to insert the solid microneedles into the biological tissue, meets or exceeds a predetermined threshold.