公开(公告)号：EP2569285A1

公开(公告)日：2013-03-20

申请号：EP11719748.3

申请日：2011-05-09

申请人： Gilead Sciences, Inc.

发明人： BAKER, William, R. ,  CAI, Shaopei ,  KAPLAN, Joshua, Aaron ,  KIM, Musong ,  LOYER-DREW, Jennifer, Alissa ,  PERREAULT, Stephane ,  PHILLIPS, Gary ,  PURVIS, Lafe, J., II ,  STASIAK, Marcin ,  STEVENS, Kirk, L. ,  VAN VELDHUIZEN, Josh

IPC分类号： C07D215/54 ,  C07D401/12 ,  C07D409/14 ,  C07D413/12 ,  A61K31/4706 ,  A61K31/4709 ,  A61P11/00

CPC分类号： C07D215/54 ,  C07D401/12 ,  C07D409/14 ,  C07D413/12

摘要： Provided are compounds of Formula (I): Wherein X is:(Formula (II)) or (Formula (III)) R
1 and R
2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.