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公开(公告)号：EP3577125A1
公开(公告)日：2019-12-11
申请号：EP18705239.4
申请日：2018-01-29
发明人： LAI, Chiajen , SHI, Bing , STRICKLEY, Robert, G.
IPC分类号： C07F9/6561 , A61K31/685 , A61P31/18 , A61P31/20
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2.发明授权THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT 有权采用固体支持，以改善和XA; 加工性的药学方式
公开(公告)号：EP2296633B1
公开(公告)日：2015-09-30
申请号：EP09739981.0
申请日：2009-05-01
发明人： KOZIARA, Joanna, M. , MENNING, Mark, M. , OLIYAI, Reza , STRICKLEY, Robert, G. , YU, Richard , KEARNEY, Brian, P. , MATHIAS, Anita, A.
IPC分类号： A61K9/20 , A61K31/47 , A61K31/513 , A61K31/5377 , A61K45/06 , A61P31/18 , A61P43/00
CPC分类号： A61K9/2086 , A61K9/1611 , A61K9/2009 , A61K9/2054 , A61K9/2077 , A61K9/4866 , A61K31/00 , A61K31/5377 , A61K2300/00
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公开(公告)号：EP2726460A1
公开(公告)日：2014-05-07
申请号：EP12735394.4
申请日：2012-06-29
发明人： CANNIZZARO, Carina, E. , GRAUPE, Michael , GUERRERO, Juan, A. , LU, Yafan , STRICKLEY, Robert, G. , VENKATARAMANI, Chandrasekar , ZABLOCKI, Jeff
IPC分类号： C07D213/64 , A61K31/4418 , A61P25/30 , A61P25/32 , A61P25/34 , A61P25/36
CPC分类号： A61K31/675 , A61K31/4418 , C07D213/64 , C07F9/581 , C07F9/584
摘要： Disclosed are novel compounds having the structure of Formula (I) : which are useful for treating mammals for dependence upon substances of addiction, for example addiction to a dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and/or alcohol. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of a compound of Formula (I) and methods of using the compounds of Formula (I) in the treatment of addiction to a dopamine-producing agent.
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公开(公告)号：EP4424374A3
公开(公告)日：2024-11-06
申请号：EP24173808.7
申请日：2018-01-29
发明人： LAI, Chiajen , SHI, Bing , STRICKLEY, Robert, G.
IPC分类号： C07F9/6561 , A61K31/685 , A61P31/18 , A61P31/20 , C07C63/38
摘要： The present invention relates to novel crystalline forms of salts and/or co-crystals of tenofovir alafenamide, the pharmaceutical formulations, and the therapeutic uses thereof in treating viral infections.
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5.发明公开THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT 有权采用固体支持，以改善和XA; 加工性的药学方式
公开(公告)号：EP2296633A2
公开(公告)日：2011-03-23
申请号：EP09739981.0
申请日：2009-05-01
发明人： KOZIARA, Joanna, M. , MENNING, Mark, M. , OLIYAI, Reza , STRICKLEY, Robert, G. , YU, Richard , KEARNEY, Brian, P. , MATHIAS, Anita, A.
IPC分类号： A61K9/20
CPC分类号： A61K9/2086 , A61K9/1611 , A61K9/2009 , A61K9/2054 , A61K9/2077 , A61K9/4866 , A61K31/00 , A61K31/5377 , A61K2300/00
摘要： The invention provides a composition comprising, a compound of formula (I) or a pharmaceutically acceptable salt thereof and a plurality of solid carrier particles, as well as methods for using the composition to inhibit the activity of cytochrome P-450.
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公开(公告)号：EP4424374A2
公开(公告)日：2024-09-04
申请号：EP24173808.7
申请日：2018-01-29
发明人： LAI, Chiajen , SHI, Bing , STRICKLEY, Robert, G.
IPC分类号： A61P31/20
CPC分类号： C07F9/65616 , A61K31/675 , A61P31/18 , A61P31/20
摘要： The present invention relates to novel crystalline forms of salts and/or co-crystals of tenofovir alafenamide, the pharmaceutical formulations, and the therapeutic uses thereof in treating viral infections.
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公开(公告)号：EP2726460B1
公开(公告)日：2015-09-23
申请号：EP12735394.4
申请日：2012-06-29
发明人： CANNIZZARO, Carina, E. , GRAUPE, Michael , GUERRERO, Juan, A. , LU, Yafan , STRICKLEY, Robert, G. , VENKATARAMANI, Chandrasekar , ZABLOCKI, Jeff
IPC分类号： C07D213/64 , A61K31/4418 , A61P25/30 , A61P25/32 , A61P25/34 , A61P25/36
CPC分类号： A61K31/675 , A61K31/4418 , C07D213/64 , C07F9/581 , C07F9/584
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