公开(公告)号：EP4085933A3

公开(公告)日：2023-01-11

申请号：EP22162958.7

申请日：2017-04-12

申请人： Ginkgo Bioworks, Inc.

发明人： Bowman, Brian R. ,  Blodgett, Joshua A.V. ,  Verdine, Gregory L. ,  Gray, Daniel C. ,  Morgenstern, Jay P. ,  Foulston, Lucy ,  Robison, Keith

IPC分类号： A61K48/00 ,  C07D307/33 ,  C07K14/035 ,  C07K14/36 ,  C12N9/02 ,  C12N15/52 ,  C12N15/76 ,  C12P35/00

摘要： The present disclosure provides nucleic acids encoding a Large ATP-binding regulator of the LuxR family (LAL) of transcription factors, vectors and host cells including such nucleic acids, and methods for producing compounds (e.g., polyketides or β-lactam compounds) with such nucleic acids, vectors, and/or host cells.

公开(公告)号：EP4085933A2

公开(公告)日：2022-11-09

申请号：EP22162958.7

申请日：2017-04-12

申请人： Ginkgo Bioworks, Inc.

发明人： Bowman, Brian R. ,  Blodgett, Joshua A.V. ,  Verdine, Gregory L. ,  Gray, Daniel C. ,  Morgenstern, Jay P. ,  Foulston, Lucy ,  Robison, Keith

IPC分类号： A61K48/00 ,  C07D307/33 ,  C07K14/035 ,  C07K14/36 ,  C12N9/02 ,  C12N15/52 ,  C12N15/76 ,  C12P35/00

摘要： The present disclosure provides nucleic acids encoding a Large ATP-binding regulator of the LuxR family (LAL) of transcription factors, vectors and host cells including such nucleic acids, and methods for producing compounds (e.g., polyketides or β-lactam compounds) with such nucleic acids, vectors, and/or host cells.