专利检索 ap:("GlaxoSmithKline istrazivacki centar Zagreb d.o.o.") AND inv:"CEMPUH KLONKAY, Andreja" 第 1 页

1.

发明公开
BIS-(COUMARIN) COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY 审中-公开
标题翻译：双（香豆素）的化合物具有抗炎作用

公开(公告)号：EP1846387A2

公开(公告)日：2007-10-24

申请号：EP06765427.7

申请日：2006-01-13

申请人： GlaxoSmithKline istrazivacki centar Zagreb d.o.o.

发明人： HUTINEC, Antun , RUPCIC, Renata , CEMPUH KLONKAY, Andreja , BOSNJAK, Berislav , FILIPOVIC SUCIC, Anita , MARKOVIC, Stribor , HRVACIC, Boska , MALNAR, Ivica , MERCEP, Mladen , MESIC, Milan , ELENKOV, Ivaylo Jivkov

IPC分类号： C07D311/56 , C07D493/12 , C07D405/14 , C07D407/14 , C07D409/14 , A61P29/00 , A61P11/06 , A61K31/37 , C07D493/14

CPC分类号： C07D413/12 , A61K47/545 , C07D311/56 , C07D407/06 , C07D407/14 , C07D413/14 , C07H17/00 , C07H17/08

摘要： Certain bis-(coumarin) compounds of formula (VI) as well as the products of thei intramolecular cyclization including pharmaceutically acceptable salts, hydrates, solvates, clathrates, prodrugs, tautomers and stereoisomers thereof are disclosed. Certain processes and intermediates for the preparation of certain bis-(coumarin) compounds, as well as for the use of these compounds as therapeutically active agents in the prophylaxis and treatment of asthma and other inflammatory diseases and conditions in mammals, especially humans are also disclosed.