专利检索 ap:("Glenmark Pharmaceuticals S.A.") AND inv:"BACK, Jonathan" 第 1 页

1.

发明公开
CD3/CD38 T CELL RETARGETING HETERO-DIMERIC IMMUNOGLOBULINS AND METHODS OF THEIR PRODUCTION 审中-公开
标题翻译： CD3 / CD38 T细胞重新获得异源二聚体免疫球蛋白及其生产方法

公开(公告)号：EP3215541A1

公开(公告)日：2017-09-13

申请号：EP15790129.9

申请日：2015-11-03

申请人： Glenmark Pharmaceuticals S.A.

发明人： OLLIER, Romain , HOU, Samuel , LISSILAA, Rami , SKEGRO, Darko , BACK, Jonathan

IPC分类号： C07K16/46 , C07K16/28 , A61K39/395

CPC分类号： C07K16/468 , A61K39/39558 , A61K2039/505 , C07K16/2809 , C07K16/2896 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/524 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/75 , C07K2317/76 , C07K2317/94

摘要： The present invention relates to hetero-dimeric immunoglobulins that target both a component of the human CD3 antigen and a component of the human CD38 antigen and methods of making the same. The present invention also relates to antibodies which bind to the human CD38 antigen and derivatives thereof for use as therapeutic or diagnostic reagents and methods of making the same.

摘要翻译： 本发明涉及同时靶向人CD3抗原成分和人CD38抗原成分的异二聚免疫球蛋白及其制备方法。本发明还涉及与人CD38抗原及其衍生物结合用作治疗或诊断试剂的抗体及其制备方法。