ANTIBODIES THAT BIND TO TL1A AND THEIR USES
    2.
    发明公开
    ANTIBODIES THAT BIND TO TL1A AND THEIR USES 审中-公开
    安全TL1A BINDENDE ANTKERRPER DEREN VERWENDUNGEN

    公开(公告)号:EP2941302A1

    公开(公告)日:2015-11-11

    申请号:EP13811986.2

    申请日:2013-12-23

    摘要: The present invention relates to antibodies or fragments thereof that bind to TL1A. More specifically, the present invention relates to an antibody or fragment thereof that binds to TL1A comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 51, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 52, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 53; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 54, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 55 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 56.

    摘要翻译: 本发明涉及与TL1A结合的抗体或其片段。 更具体地,本发明涉及结合TL1A的抗体或其片段,其包含包含SEQ ID NO:51的氨基酸序列的重链CDR1和/或包含SEQ ID NO:51的氨基酸序列的重链CDR2 :52,和/或包含SEQ ID NO:53的氨基酸序列的重链CDR3; 和/或包含包含SEQ ID NO:54的氨基酸序列的轻链CDR1和/或包含SEQ ID NO:55的氨基酸序列的轻链CDR2和/或包含氨基酸序列的轻链CDR3 的SEQ ID NO:56。

    ANTIBODIES THAT BIND TO CCR6 AND THEIR USES
    6.
    发明公开
    ANTIBODIES THAT BIND TO CCR6 AND THEIR USES 审中-公开
    与CCR6结合的抗体及其用途

    公开(公告)号:EP3207060A1

    公开(公告)日:2017-08-23

    申请号:EP15781677.8

    申请日:2015-10-19

    IPC分类号: C07K16/28 A61K39/00

    摘要: The present invention relates to antibodies or fragments thereof that bind to CCR6. More specifically, the present invention relates to an antibody or fragment thereof that binds to CCR6 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 31, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 32, SEQ ID NO: 190, SEQ ID NO: 239, SEQ ID NO: 240, SEQ ID NO: 241, SEQ ID NO: 242, SEQ ID NO: 254 or SEQ ID NO: 255 and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 33; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 34, SEQ ID NO: 191, SEQ ID NO:244, SEQ ID NO:245, SEQ ID NO: 246 or SEQ ID NO: 256, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 35, SEQ ID NO: 247, SEQ ID NO: 248 or SEQ ID NO:257 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 36 or SEQ ID NO: 192 or SEQ ID NO: 193.

    摘要翻译: 本发明涉及与CCR6结合的抗体或其片段。 更具体地,本发明涉及结合CCR6的抗体或其片段,所述CCR6包含含有SEQ ID NO:31的氨基酸序列的重链CDR1和/或含有SEQ ID NO:31的氨基酸序列的重链CDR2 :32,SEQ ID NO:190,SEQ ID NO:239,SEQ ID NO:240,SEQ ID NO:241,SEQ ID NO:242,SEQ ID NO:254或SEQ ID NO:255和/或重链 包含SEQ ID NO:33的氨基酸序列的CDR3; 和/或包含含有SEQ ID NO:34,SEQ ID NO:191,SEQ ID NO:244,SEQ ID NO:245,SEQ ID NO:246或SEQ ID NO:256的氨基酸序列的轻链CDR1, 和/或包含SEQ ID NO:35,SEQ ID NO:247,SEQ ID NO:248或SEQ ID NO:257的氨基酸序列的轻链CDR2和/或包含SEQ ID NO:35的氨基酸序列的轻链CDR3 ID NO:36或SEQ ID NO:192或SEQ ID NO:193。