-
1.
公开(公告)号:EP3525766A1
公开(公告)日:2019-08-21
申请号:EP17790926.4
申请日:2017-10-12
IPC分类号: A61K9/20 , A61K31/4439 , A61P7/06 , A61P11/00
-
2.
公开(公告)号:EP4461357A2
公开(公告)日:2024-11-13
申请号:EP24197031.8
申请日:2017-10-12
IPC分类号: A61P11/00
摘要: Provided herein are high strength/high drug load tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde ("Compound 1"), dispersible tablets comprising Compound 1, processes of manufacturing such tablets, and methods for treating patients with the tablets. Compound 1 is useful for treating hematological disorders such as sickle cell disease, pulmonary disease such as idiopathic pulmonary fibrosis, and hypoxia and hypoxemia conditions.
-
3.
公开(公告)号:EP3383392A1
公开(公告)日:2018-10-10
申请号:EP16813299.1
申请日:2016-12-02
IPC分类号: A61K31/4439 , A61K9/48 , A61P35/02
CPC分类号: A61K31/4439 , A61K9/1605 , A61K9/4858 , A61K9/4866
摘要: Provided herein are methods for treating sickle cell disease, comprising administering to a subject 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)-methoxy)benzaldehyde (Compound 1), or a polymorph thereof, in certain dosing regimens.
-
-