公开(公告)号：EP4461357A2

公开(公告)日：2024-11-13

申请号：EP24197031.8

申请日：2017-10-12

申请人： Global Blood Therapeutics, Inc.

发明人： DALZIEL, Sean Mark ,  BEJUGAM, Naveen ,  HABIBIZAD, Nazila ,  KOMEYLI, Ali ,  LEUNG, DeMei

IPC分类号： A61P11/00

摘要： Provided herein are high strength/high drug load tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde ("Compound 1"), dispersible tablets comprising Compound 1, processes of manufacturing such tablets, and methods for treating patients with the tablets. Compound 1 is useful for treating hematological disorders such as sickle cell disease, pulmonary disease such as idiopathic pulmonary fibrosis, and hypoxia and hypoxemia conditions.

公开(公告)号：EP3525766A1

公开(公告)日：2019-08-21

申请号：EP17790926.4

申请日：2017-10-12

申请人： Global Blood Therapeutics, Inc.

发明人： DALZIEL, Sean Mark ,  BEJUGAM, Naveen ,  HABIBIZAD, Nazila ,  KOMEYLI, Ali ,  LEUNG, DeMei

IPC分类号： A61K9/20 ,  A61K31/4439 ,  A61P7/06 ,  A61P11/00