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公开(公告)号：EP2970184A1
公开(公告)日：2016-01-20
申请号：EP14768759.4
申请日：2014-03-10
IPC分类号： C07D401/04 , C07D403/04 , A61K31/4439 , A61K31/4155
CPC分类号： C07D401/04
摘要： Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
摘要翻译： 本文提供适合作为血红蛋白调节剂的化合物和药物组合物，其制备方法和中间体，以及它们用于治疗由血红蛋白介导的病症和将受益于组织和/或细胞氧合的病症的方法。
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公开(公告)号：EP2970184B1
公开(公告)日：2018-12-05
申请号：EP14768759.4
申请日：2014-03-10
IPC分类号： C07D401/04 , C07D403/04 , A61K31/4439 , A61K31/4155
CPC分类号： C07D401/04
摘要： Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
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公开(公告)号：EP2970196A1
公开(公告)日：2016-01-20
申请号：EP14770695.6
申请日：2014-03-10
发明人： XU, Qing , LI, Zhe , GWALTNEY II, Stephen L.
IPC分类号： C07D401/12 , C07D207/08 , C07D211/08 , C07D211/20 , A61K31/4427 , A61P7/00
CPC分类号： C07D403/12 , C07D207/08 , C07D211/30 , C07D265/30 , C07D401/12
摘要： Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
摘要翻译： 本文提供适合作为血红蛋白调节剂的化合物和药物组合物，其制备方法和中间体，以及它们用于治疗由血红蛋白介导的病症和将受益于组织和/或细胞氧合的病症的方法。
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公开(公告)号：EP2970196B1
公开(公告)日：2020-11-25
申请号：EP14770695.6
申请日：2014-03-10
发明人： XU, Qing , LI, Zhe , GWALTNEY II, Stephen L.
IPC分类号： C07D487/04 , A61K31/437 , A61P7/00 , C07D401/14 , C07D401/04 , C07C65/30 , C07D231/56 , C07D471/04 , C07D257/04 , C07D211/62 , C07D213/30 , C07D401/12 , C07D213/64 , C07D403/12 , C07D265/30 , C07D207/08 , C07D211/30
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