-
公开(公告)号：EP1551831A4
公开(公告)日：2008-05-14
申请号：EP03751582
申请日：2003-10-17
发明人： KIM NAM DU , LEE JAE HEON , LEE MOON SUB , CHANG YOUNG KIL , LEE GWAN SUN
IPC分类号： C07D413/14 , C07D471/04
CPC分类号： C07D471/04
摘要： Risperidone is prepared in a high yield by reacting 2,4-difluorophenyl(4-piperidinyl)methanone oxime hydrochloride and 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one in an aqueous alkali hydroxide solution having an alkali hydroxide concentration in the range of 20 to 40%.
-
2.发明公开PROCESS FOR PREPARING 7-AMINO-3-METHOXYMETHYL-3-CEPHEM-4-CARBOXYLIC ACID 有权PROCESS FOR 7-氨基-3-甲氧基甲基-3-头孢烯-4-羧酸的制备
公开(公告)号：EP1220859A4
公开(公告)日：2003-04-02
申请号：EP00970265
申请日：2000-10-13
发明人： LEE GWAN SUN , LEE JAE HEON , CHANG YOUNG KIL , PARK CHUL HYUN , PARK GHA SEUNG , KIM CHEOL KYUNG
IPC分类号： C07D501/04 , C07B61/00 , C07D501/00 , C07D501/22
CPC分类号： C07D501/00
摘要： 7-amino-3-methoxymethyl-3-cephem-4-carboxylic acid of formula (I) can be easily prepared by reacting 7-aminocephalosporanic acid of formula (II) with an azeotropic mixture of trimethyl borate and methanol in the presence of methanesulfonic acid.
-
公开(公告)号：EP2661438A4
公开(公告)日：2014-06-11
申请号：EP11854581
申请日：2011-12-29
发明人： SON JUNG BEOM , KIM NAM DU , CHANG YOUNG KIL , KIM HEE CHEOL , KIM JI SOOK , JUNG YOUNG HEE
IPC分类号： C07D487/04 , A61K31/519 , A61P3/00 , A61P3/04 , A61P3/10 , C07D495/04
CPC分类号： C07D495/04 , C07D487/04
-
4.发明公开PROCESS FOR THE SELECTIVE PREPARATION OF 3-(Z) PROPENYL-CEPHEM COMPOUND 审中-公开用于3-（Z）选择性地制备过程-PROPENYLCEPHEMVERBINDUNG
公开(公告)号：EP1379530A4
公开(公告)日：2008-04-02
申请号：EP02720650
申请日：2002-04-17
发明人： LEE GWAN SUN , CHANG YOUNG KIL , KIM HONG SUN , LEE JAE HEON , PARK CHUL HYUN , PARK GHA SEUNG , KIM CHEOL KYUNG
IPC分类号： C07D501/22 , A61K31/545 , A61P31/04 , C07D501/00 , C07D501/04
CPC分类号： C07D501/00 , Y02P20/55
摘要： A 3-(Z)-propenyl cephem compound is selectively prepared by reacting a phosphoranylidene cephemcompound with acetaldehyde in the presence of a base in a solvent mixture comprising diethyl ether, formula (I), wherein R is a carboxyl protecting group; R1 is hydrogen or R2CH2CO-; and R2 is ethyl, 2-thiophenyl, phenyl, p-hydroxyphenyl or phenoxy.
-
5.发明公开CRYSTALLINE ACID SALTS OF CEFDINIR AND PROCESS FOR PREPARING CEFDINIR USING SAME 有权KRISTALLINESÄURESALZEVON CEFDINIR UND VERFAHREN ZUR HERSTELLUNG VON CEFDINIR UNTER DEREN VERWENDUNG
公开(公告)号：EP1392703A4
公开(公告)日：2004-10-27
申请号：EP02730990
申请日：2002-06-05
发明人： LEE GWAN SUN , CHANG YOUNG KIL , KIM HONG SUN , PARK CHUL HUYN , PARK GHA SEUNG , KIM CHEOL KYUNG
IPC分类号： C07B61/00 , C07D501/00 , C07D501/14 , C07D501/22
CPC分类号： C07D501/00
摘要： High purity cefdinir is prepared in a high yield by a process comprising the steps of: treating a cefdinir intermediate with a formic acid-sulfuric acid mixture or a formic acid-methanesulfonic acid mixture to obtain a crystalline salt of cefdinir and reacting the crystalline salt with a base in a solvent.
摘要翻译： 通过包括以下步骤的方法以高收率制备高纯度头孢地尼：用甲酸 - 硫酸混合物或甲酸 - 甲磺酸混合物处理头孢地尼中间体以获得头孢地尼的结晶盐，并使该结晶盐与 在溶剂中的碱。
-
公开(公告)号：EP1228074A4
公开(公告)日：2003-02-26
申请号：EP00976419
申请日：2000-11-07
发明人： LEE GWAN SUN , CHANG YOUNG KIL , LEE JAE HEON , PARK CHUL HYUN , PARK GHA SEUNG , JUNG KEUM SHIN
IPC分类号： C07B61/00 , C07D501/00 , C07D501/34 , C07D501/36
CPC分类号： C07D501/00
摘要： Highly pure cefpodoxime proxetil can be prepared by a simple process comprising the step of reacting a cefpodoxime salt with 1-iodoethylisopropylcarbonate in an organic solvent in the presence of a crown ether.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.01 秒)
