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1.发明公开THYROXINE/CYCLODEXTRIN COMPLEXES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 失效甲状腺素/ ZYKLODEXTRINKOMPLEXE及其药物制剂
公开(公告)号：EP0814844A2
公开(公告)日：1998-01-07
申请号：EP96941051.0
申请日：1996-11-28
申请人： HEXAL AG
发明人： FISCHER, Wilfried , BRACHER, Daniel
CPC分类号： A61K9/7061 , A61K9/7084 , A61K31/198 , A61K47/6951 , B82Y5/00
摘要： Thyroxine containing pharmaceutical compositions with improved aqueous solubility, stability and enhanced membrane permeation have been prepared by formulating thyroxine with cyclodextrins. These thyroxine/cyclodextrin complexes can further be transformed into different dosage forms (oral tablets, injectables, transdermal patches, hydrogels, ointments, suppositories, etc.) by employing known, common pharmaceutical additives.
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公开(公告)号：EP0835100A1
公开(公告)日：1998-04-15
申请号：EP96919764.0
申请日：1996-05-10
申请人： HEXAL AG
发明人： FISCHER, Wilfried , BRACHER, Daniel
IPC分类号： A61K9
CPC分类号： A61K31/522 , A61K9/127
摘要： The invention concerns an aqueous pharmaceutical preparation intended for topical application and containing aciclovir or an aciclovir derivative.
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3.发明授权THYROXINE/CYCLODEXTRIN COMPLEXES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 失效甲状腺素/ ZYKLODEXTRINKOMPLEXE及其药物制剂
公开(公告)号：EP0814844B1
公开(公告)日：2002-09-04
申请号：EP96941051.3
申请日：1996-11-28
申请人： HEXAL AG
发明人： FISCHER, Wilfried , BRACHER, Daniel
IPC分类号： A61K47/48
CPC分类号： A61K9/7061 , A61K9/7084 , A61K31/198 , A61K47/6951 , B82Y5/00
摘要： Thyroxine containing pharmaceutical compositions with improved aqueous solubility, stability and enhanced membrane permeation have been prepared by formulating thyroxine with cyclodextrins. These thyroxine/cyclodextrin complexes can further be transformed into different dosage forms (oral tablets, injectables, transdermal patches, hydrogels, ointments, suppositories, etc.) by employing known, common pharmaceutical additives.
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公开(公告)号：EP0835100B1
公开(公告)日：2002-01-02
申请号：EP96919764.9
申请日：1996-05-10
申请人： HEXAL AG
发明人： FISCHER, Wilfried , BRACHER, Daniel
CPC分类号： A61K31/522 , A61K9/127
摘要： The invention concerns an aqueous pharmaceutical preparation intended for topical application and containing aciclovir or an aciclovir derivative.
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5.发明授权TRANSDERMALES THERAPEUTISCHES SYSTEM (TTS) ZUR VERABREICHUNG VON TESTOSTERON 失效透皮治疗系统（TTS）FOR DELIVERY睾酮
公开(公告)号：EP0825865B1
公开(公告)日：2001-11-07
申请号：EP96919765.6
申请日：1996-05-10
申请人： HEXAL AG
发明人： FISCHER, Wilfried , BRACHER, Daniel
IPC分类号： A61K31/565 , A61K9/70
CPC分类号： A61K31/568 , A61K9/703 , A61K9/7084 , A61K47/6951 , B82Y5/00
摘要： The invention concerns a transdermal therapeutic system for administering testosterone or a testosterone derivative as the active substance.
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6.发明公开TRANSDERMALES THERAPEUTISCHES SYSTEM (TTS) ZUR VERABREICHUNG VON TESTOSTERON 失效透皮治疗系统（TTS）FOR DELIVERY睾酮
公开(公告)号：EP0825865A1
公开(公告)日：1998-03-04
申请号：EP96919765.0
申请日：1996-05-10
申请人： HEXAL AG
发明人： FISCHER, Wilfried , BRACHER, Daniel
CPC分类号： A61K31/568 , A61K9/703 , A61K9/7084 , A61K47/6951 , B82Y5/00
摘要： The invention concerns a transdermal therapeutic system for administering testosterone or a testosterone derivative as the active substance.
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