专利检索 ap:("HIGH POINT PHARMACEUTICALS LLC") AND inv:"KOSTURA MATTHEW" 第 1 页

1.

发明公开
TRICYCLIC COMPOUNDS AS MODULATORS OF TNF- SYNTHESIS AND AS PDE4 INHIBITORS 有权
标题翻译：三环化合物作为TNF-α合成的调节剂和作为PDE4抑制剂的

公开(公告)号：EP2244574A4

公开(公告)日：2012-01-11

申请号：EP09704760

申请日：2009-01-23

申请人： HIGH POINT PHARMACEUTICALS LLC

发明人： MJALLI ADNAN M M , GADDAM BAPU , POLISETTI DHARMA RAO , KOSTURA MATTHEW , GUZEL MUSTAFA

IPC分类号： C07D239/42 , A01N43/54 , A61K31/505

CPC分类号： A61K31/519 , C07D471/04

摘要： The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-alpha or by PDE4, including but not limited to rheumatoid arthritis.