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1.发明授权NOVEL 2-(2-HYDROXYPHENYL) BENZOTHIADIAZINES USEFUL FOR TREATING OBESITY AND DIABETES 有权NEW肥胖和糖尿病SUITABLE的处理2-（2-羟基苯基）Benzothiadiazines
公开(公告)号：EP2086951B1
公开(公告)日：2011-12-21
申请号：EP07822643.8
申请日：2007-11-15
发明人： OLESEN, Preben Houlberg , PETERSEN, Anders Klarskov , NIELSEN, Flemming Elmelund , CHRISTIANSEN, Lise Brown , HANSEN, Holger Claus
IPC分类号： C07D285/24 , A61K31/549 , A61P3/04
CPC分类号： C07D285/24
摘要： The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
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2.发明授权NOVEL 2-(2-HYDROXYPHENYL)BENZIMIDAZOLES USEFUL FOR TREATING OBESITY AND DIABETES 有权NEW 2-（2-羟基苯基）苯并咪唑参与肥胖和糖尿病的治疗是合适的
公开(公告)号：EP2097388B1
公开(公告)日：2011-09-07
申请号：EP07847181.0
申请日：2007-11-15
发明人： OLESEN, Preben Houlberg , PETERSEN, Anders Klarskov , NIELSEN, Flemming Elmelund , CHRISTIANSEN, Lise Brown , HANSEN, Holger Claus
IPC分类号： C07D235/18 , A61K31/4184 , A61P3/04 , A61P3/10
CPC分类号： C07D235/18
摘要： The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
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3.发明公开NOVEL 2-(2-HYDROXYPHENYL) BENZOTHIADIAZINES USEFUL FOR TREATING OBESITY AND DIABETES 有权NEW肥胖和糖尿病SUITABLE的处理2-（2-羟基苯基）Benzothiadiazines
公开(公告)号：EP2086951A1
公开(公告)日：2009-08-12
申请号：EP07822643.8
申请日：2007-11-15
发明人： OLESEN, Preben Houlberg , PETERSEN, Anders Klarskov , NIELSEN, Flemming Elmelund , CHRISTIANSEN, Lise Brown , HANSEN, Holger Claus
IPC分类号： C07D285/24 , A61K31/549 , A61P3/04
CPC分类号： C07D285/24
摘要： The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
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4.发明公开2- ( 2 -HYDROXYPHENYL) -QUINAZOLIN-4-ONES USEFUL FOR TREATING OBESITY AND DIABETES 审中-公开2-（2-羟基苯基） - 喹唑啉-4-酮，对肥胖症和糖尿病的治疗是合适的
公开(公告)号：EP2097391A1
公开(公告)日：2009-09-09
申请号：EP07822642.0
申请日：2007-11-15
发明人： OLESEN, Preben Houlberg , PETERSEN, Anders Klarskov , NIELSEN, Flemming Elmelund , CHRISTIANSEN, Lise Brown , HANSEN, Holger Claus
IPC分类号： C07D239/91 , A61K31/517 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/12
CPC分类号： C07D239/91
摘要： The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
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5.发明公开NOVEL 2-(2-HYDROXYPHENYL)BENZIMIDAZOLES USEFUL FOR TREATING OBESITY AND DIABETES 有权NEW 2-（2-羟基苯基）苯并咪唑参与肥胖和糖尿病的治疗是合适的
公开(公告)号：EP2097388A1
公开(公告)日：2009-09-09
申请号：EP07847181.0
申请日：2007-11-15
发明人： OLESEN, Preben Houlberg , PETERSEN, Anders Klarskov , NIELSEN, Flemming Elmelund , CHRISTIANSEN, Lise Brown , HANSEN, Holger Claus
IPC分类号： C07D235/18 , A61K31/4184 , A61P3/04 , A61P3/10
CPC分类号： C07D235/18
摘要： The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
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6.发明公开NEW HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES 审中-公开新的卤代烷基取代的化合物可用于治疗肥胖和糖尿病
公开(公告)号：EP2097380A1
公开(公告)日：2009-09-09
申请号：EP07847179.4
申请日：2007-11-15
发明人： OLESEN, Preben Houlberg , PETERSEN, Anders Klarskov , NIELSEN, Flemming Elmelund , CHRISTIANSEN, Lise Brown
IPC分类号： C07D213/56 , C07D261/08 , A61K31/5355 , A61P3/04
CPC分类号： C07D261/08 , C07D213/56
摘要： The present invention relates to novel compounds of formula [I], wherein R1 represernts heteroaryl, at least one substituent among R5, R6 and R7 represent -SR12, -S(O)R12 or -S(O)2R12 and the remaining substituents are as defined in the claims, that act as chemical uncouplers. Compounds of the invention are useful inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases associated therewith.
摘要翻译： 本发明涉及新的式[I]化合物，其中R 1表示杂芳基，R 5，R 6和R 7中的至少一个取代基表示-SR 12，-S（O）R 12或-S（O）2 R 12，其余取代基为 如权利要求中所定义的那样，起到化学解偶联剂的作用。 本发明化合物尤其可用于治疗（包括预防）肥胖症，糖尿病和一些与之相关的疾病。
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