公开(公告)号：EP3925606A1

公开(公告)日：2021-12-22

申请号：EP20755904.8

申请日：2020-01-23

申请人： Hisamitsu Pharmaceutical Co., Inc.

发明人： KUROKAWA Takao ,  ARAKI Hiroyuki ,  KOMATANI Kimiko

IPC分类号： A61K31/381 ,  A61P25/14 ,  A61P25/16 ,  A61K9/70 ,  A61K47/06 ,  A61K47/10 ,  A61K47/22 ,  A61K47/32

摘要： The present invention provides a rotigotine stabilization method for stabilizing rotigotine and/or a pharmaceutically acceptable salt thereof in a rotigotine-containing patch comprising a backing layer and an adhesive agent layer, the adhesive agent layer containing the rotigotine and/or the pharmaceutically acceptable salt thereof and a styrene-based thermoplastic elastomer, the method comprising further incorporating cross-linked polyvinylpyrrolidone in the adhesive agent layer in a content of 3 to 25% by mass in the adhesive agent layer.