公开(公告)号：EP2564923A1

公开(公告)日：2013-03-06

申请号：EP11775110.7

申请日：2011-04-28

申请人： Hitachi High-Technologies Corporation

发明人： NUNOSHIGE, Jun ,  KAGAWA, Hiroyuki ,  ITO, Shinya ,  KANDA, Katsuhiro ,  WAKI, Izumi ,  ARAYA, Kotaro ,  TAMURA, Terumi

IPC分类号： B01J20/281 ,  G01N30/88

CPC分类号： B01J20/285 ,  B01J2220/62 ,  B01J2220/82 ,  G01N30/7233

摘要： An adsorbent that enables solid phase extraction with high efficiency and good selectivity of solutes having a broad chromatographic polarity range including high-polarity solute molecules while suppressing adsorption of impurities, and a solid phase extraction method therefor are provided. A heterocyclic-ring-containing copolymer adsorbent that is provided herein comprises a copolymer that comprises: a multifunctional heterocyclic-ring-containing monomer having a heterocyclic ring containing at least two heteroatoms in the ring system; and a monomer that is copolymerizable with the multifunctional heterocyclic-ring-containing monomer, wherein the multifunctional heterocyclic ring constitutes the main chain structure. Furthermore, the solid phase extraction method comprises a step of bringing a solution containing any one of a low-polarity solute molecule, a moderate-polarity solute molecule, and a high-polarity solute molecule as a solute into contact with the heterocyclic-ring-containing copolymer adsorbent, so that one or more types of solute are selectively adsorbed and held.

摘要翻译： 提供一种吸附剂，其能够高效率地进行固相萃取，并且具有宽的色谱极性范围的溶质的选择性，包​​括高极性溶质分子同时抑制杂质的吸附，以及其固相萃取方法。 本文提供的含杂环共聚物吸附剂包括共聚物，其包含：具有在环系中含有至少两个杂原子的杂环的多官能含杂环单体; 和可与含多官能杂环的单体共聚的单体，其中多官能杂环构成主链结构。 此外，固相萃取方法包括使含有低极性溶质分子，中等极性溶质分子和高极性溶质分子中的任一种的溶液作为溶质与杂环 - 含有共聚物吸附剂，使得一种或多种类型的溶质被选择性吸附和保持。