公开(公告)号：EP4132347A1

公开(公告)日：2023-02-15

申请号：EP21720180.5

申请日：2021-04-07

申请人： Humanitas Mirasole S.p.A.

发明人： DONI, Andrea ,  MORONE, Diego

IPC分类号： A61B5/00 ,  G01N21/64 ,  G01N33/573

公开(公告)号：EP3897688A2

公开(公告)日：2021-10-27

申请号：EP19832342.0

申请日：2019-12-18

申请人： Humanitas Mirasole S.p.A. ,  Humanitas University

发明人： DONI, Andrea ,  MANTOVANI, Alberto

IPC分类号： A61K38/17 ,  A61P31/10

公开(公告)号：EP1966612B1

公开(公告)日：2010-03-24

申请号：EP06829691.2

申请日：2006-12-18

申请人： Humanitas Mirasole S.p.A.

发明人： MANTOVANI, Alberto ,  GARLANDA, Cecilia ,  DONI, Andrea ,  CETIN, Irene

IPC分类号： G01N33/68

CPC分类号： G01N33/689 ,  C07K16/24 ,  G01N33/543 ,  G01N2333/4715 ,  G01N2800/368 ,  G01N2800/50 ,  G01N2800/7095

摘要： The present invention relates to a diagnostic test for inflammatory endothelial dysfunctions in pregnant women. Particularly, the present invention relates to a method of diagnosing or evaluating the risk of contracting an inflammatory endothelial dysfunction of the maternal compartment comprising the following steps: a) detecting the plasma levels of long pentraxin PTX3 in blood samples taken from a pregnant woman; b) comparing the PTX3 plasma level data, obtained according to step a) , with statistically significant PTX3 plasma level data of normal pregnant population.

公开(公告)号：EP1966612A1

公开(公告)日：2008-09-10

申请号：EP06829691.2

申请日：2006-12-18

申请人： Humanitas Mirasole S.p.A.

发明人： MANTOVANI, Alberto ,  GARLANDA, Cecilia ,  DONI, Andrea ,  CETIN, Irene

IPC分类号： G01N33/68

CPC分类号： G01N33/689 ,  C07K16/24 ,  G01N33/543 ,  G01N2333/4715 ,  G01N2800/368 ,  G01N2800/50 ,  G01N2800/7095

摘要： The present invention relates to a diagnostic test for inflammatory endothelial dysfunctions in pregnant women. Particularly, the present invention relates to a method of diagnosing or evaluating the risk of contracting an inflammatory endothelial dysfunction of the maternal compartment comprising the following steps: a) detecting the plasma levels of long pentraxin PTX3 in blood samples taken from a pregnant woman; b) comparing the PTX3 plasma level data, obtained according to step a) , with statistically significant PTX3 plasma level data of normal pregnant population.

公开(公告)号：EP3669885A1

公开(公告)日：2020-06-24

申请号：EP18214853.6

申请日：2018-12-20

申请人： Humanitas Mirasole S.p.A. ,  Humanitas University

发明人： DONI, Andrea ,  MANTOVANI, Alberto

IPC分类号： A61K38/17 ,  A61P31/10

摘要： This invention relates to the use of Serum Amyloid P component (SAP) polypeptides for the treatment of Eurotiomycetes fungi infections, in particular for aspergillosis and invasive aspergillosis, alone or in combination with pentraxin-3 (PTX3) polypeptides.