公开(公告)号：EP3777890A1

公开(公告)日：2021-02-17

申请号：EP20187452.6

申请日：2015-11-06

申请人： II, Masaaki ,  Foundation for Biomedical Research and Innovation at Kobe

发明人： II, Masaaki ,  TABATA, Yasuhiko

IPC分类号： A61K45/00 ,  A61K9/16 ,  A61K9/51 ,  A61K31/366 ,  A61K35/12 ,  A61K47/34 ,  A61P9/10 ,  A61P43/00 ,  A61K35/26

摘要： The present invention is directed to a stem cell with an enhanced function, the stem cell comprising a statin-included nanoparticle preparation for enhancing a function of the stem cell, the statin-included nanoparticle preparation comprising: a statin-included nanoparticle obtained by including statin in a nanoparticle, containing a bioabsorbable polymer, wherein the nanoparticle has a number average particle diameter of less than 1000 nm, and wherein the function of the stem cell which is to be enhanced is at least one of a migratory capacity, a proliferation capacity, and the production of a neovascularization factor.