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1.发明公开
公开(公告)号：EP1232246A1
公开(公告)日：2002-08-21
申请号：EP00980623.3
申请日：2000-11-21
申请人： IMMUNEX CORPORATION
CPC分类号： C07K16/28 , A61K47/6849 , A61K2039/505 , C12N5/0645
摘要： The invention is directed to purified and isolated novel CD56+ plasmacytoid monocytes, the healthy counterpart of CD4+ CD56+ cutaneous neoplasm, and uses thereof.
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2.发明授权FAMILY OF IMMUNOREGULATORS DESIGNATED LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTORS (LIR) 有权免疫调节物与NAME FAMILY“血液白细胞免疫球蛋白样受体的”（LIR）
公开(公告)号：EP1177292B1
公开(公告)日：2005-12-14
申请号：EP00928985.1
申请日：2000-05-12
申请人： IMMUNEX CORPORATION
IPC分类号： C12N15/12 , C12N15/62 , C07K14/705 , C07K19/00 , C07K16/28
CPC分类号： C07K14/70535 , A61K38/00 , C07K14/70503 , C07K2319/00
摘要： A family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
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3.发明公开FAMILY OF IMMUNOREGULATORS DESIGNATED LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTORS (LIR) 有权免疫调节物与NAME FAMILY“血液白细胞免疫球蛋白样受体的”（LIR）
公开(公告)号：EP1177292A2
公开(公告)日：2002-02-06
申请号：EP00928985.1
申请日：2000-05-12
申请人： IMMUNEX CORPORATION
IPC分类号： C12N15/12 , C12N15/62 , C07K14/705 , C07K19/00 , C07K16/28
CPC分类号： C07K14/70535 , A61K38/00 , C07K14/70503 , C07K2319/00
摘要： A family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
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4.发明授权FAMILY OF IMMUNOREGULATORS DESIGNATED LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTORS (LIR) 有权免疫调节物与NAME FAMILY“血液白细胞免疫球蛋白样受体的”（LIR）
公开(公告)号：EP1177292B8
公开(公告)日：2006-05-17
申请号：EP00928985.1
申请日：2000-05-12
申请人： IMMUNEX CORPORATION
IPC分类号： C12N15/12 , C12N15/62 , C07K14/705 , C07K19/00 , C07K16/28
CPC分类号： C07K14/70535 , A61K38/00 , C07K14/70503 , C07K2319/00
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