专利检索 ap:("IMPERIAL COLLEGE OF SCIENCE,TECHNOLOGY & MEDICINE") AND inv:"MASKELL, Duncan, John" 第 1 页

1.

发明公开
MUTANT $i(msbB) or $i(htrB) GENES 失效
标题翻译：活疫苗与突变MSBB AND / OR HTRB GEN

公开(公告)号：EP0973911A1

公开(公告)日：2000-01-26

申请号：EP98902105.0

申请日：1998-01-30

申请人： IMPERIAL COLLEGE OF SCIENCE,TECHNOLOGY & MEDICINE

发明人： MASKELL, Duncan, John , DOUGAN, Gordon,Imperial Col. of Sci., Tech. med.

IPC分类号： C12N15/52 , C07K14/195 , C12N15/63 , C12N1/20 , A61K39/02

CPC分类号： C12R1/42 , A61K39/00 , C07K14/255

摘要： Nucleic acid for a mutant msbB or htrB gene derivable from Salmonella which results in loss of an msbB or htrB encoded protein, respectively, or loss of function of the protein, which in turn results in a lipid A molecule having reduced toxicity.