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    PROCESS FOR REMOVING PESTICIDES FROM GINKGO BILOBA EXTRACTS, AND EXTRACTS OBTAINABLE BY SAID PROCESS
    6.
    发明公开
    PROCESS FOR REMOVING PESTICIDES FROM GINKGO BILOBA EXTRACTS, AND EXTRACTS OBTAINABLE BY SAID PROCESS 有权
    程序脱除从农药GINGKO-BILOBA提取物及基于该方法得到的提取物

    公开(公告)号：EP2427662A2

    公开(公告)日：2012-03-14

    申请号：EP10749776.0

    申请日：2010-03-31

    申请人： Indena S.p.A.

    发明人： GIORI, Andrea ,  MOMBELLI, Giacomo ,  ARPINI, Sabrina ,  ACERBI, Mario

    IPC分类号： F16B2/12

    CPC分类号： A61K36/16 ,  A23L5/23 ,  A61K2236/35 ,  A61K2236/53 ,  B01D9/00 ,  B01D11/0492

    摘要： Process for removing pesticides from
    Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps: a. Liquid-liquid extraction of the extract to obtain a medium polarity fraction containing ginkgo terpenes and pesticides not removable with hexane, and a high polarity fraction containing ginkgo flavone glycosides; b. crystallisation from the medium polarity fraction obtained at step a) to give an intermediate with a ginkgolide content of not less than 50%; c. crystallisation from the residual solution obtained at step b) to give an intermediate with a bilobalide content of not less than 50%; d. mixing of the high polarity fraction obtained at step a) with the ginkgo terpene intermediate and the bilobalide intermediate obtained at steps b) and c).

    摘要翻译： 一种从银杏叶提取物，其中涉及提交提取由传统方法向下述工序去除农药：一。 该提取物的液 - 液萃取，以获得中等极性馏分含有银杏萜烯和杀虫剂不可拆卸用己烷，和高极性馏分含有银杏黄酮苷; 湾 从在步骤A中获得的中等极性馏分），得到具有不小于50％的银杏内酯含量的中间结晶; 温度。 从在步骤B中获得的残留溶液），得到具有不小于50％的银杏内酯含量的中间结晶; 天。 与银杏萜中间，并在步骤B中获得的银杏内酯中间体，在步骤A中获得的高极性部分）的混合）和c）。