公开(公告)号：EP1112500B1

公开(公告)日：2004-09-22

申请号：EP99968716.3

申请日：1999-09-07

申请人： INNOGENETICS N.V.

发明人： HULSTAERT, Frank ,  VANMECHELEN, Eugeen ,  VANDERSTICHELE, Hugo ,  VAN DE VOORDE, André ,  VAN GOOL, Stefaan

IPC分类号： G01N33/68 ,  G01N33/574

CPC分类号： G01N33/6896 ,  G01N33/574

摘要： The present invention provides a new method for the early diagnosis of CNS damage in an individual, said CNS damage being caused by space-occupying lesions of the CNS, by invasion or metastasis of the CNS, by organisms, by anoxia or ischemia, by chemical agents, by physical agents, or by a combination of these mechanisms. This new method comprises the step of determining and/or quantifying the level of tau in said individual and comparing it to the level of tau in control healthy individuals.