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1.发明授权
公开(公告)号：EP3236988B1
公开(公告)日：2020-06-24
申请号：EP15817338.5
申请日：2015-12-22
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2.发明公开METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL SUPERINFECTIONS POST-INFLUENZA 审中-公开用于治疗细菌感染后超感染的方法和药物组合物
公开(公告)号：EP3236988A1
公开(公告)日：2017-11-01
申请号：EP15817338.5
申请日：2015-12-22
申请人： INSERM - Institut National de la Santé et de la Recherche Médicale , Centre National de la Recherche Scientifique (C.N.R.S.) , Université de Droit et de la Santé de Lille 2 , Université de Lille 1 Sciences et Technologies , Institut Pasteur De Lille
摘要： The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza. In particular, the present invention relates to a method of treating a bacterial superinfection post-influenza in a subject in need thereof comprising administering the subject with a therapeutically effective amount of a flagellin polypeptide optionally in combination with at least one antibiotic.
摘要翻译： 本发明涉及用于治疗流感后细菌双重感染的方法和药物组合物。 具体而言，本发明涉及在有需要的受试者中治疗流感后细菌超感染的方法，其包括向受试者施用治疗有效量的鞭毛蛋白多肽，所述鞭毛蛋白多肽任选地与至少一种抗生素组合。
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3.发明公开METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL INFECTIONS 审中-公开化合物和药物组合物对细菌感染的治疗
公开(公告)号：EP3024476A1
公开(公告)日：2016-06-01
申请号：EP14749736.6
申请日：2014-07-25
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , Université du Droit et de la Santé de Lille 2 , Centre National de la Recherche Scientifique (CNRS) , Institut Pasteur De Lille , Université de Lille 1 Sciences et Technologies , ETH Zurich , Universidad de la Republica
发明人： HARDT, Wolf-Dietrich , KAISER, Patrick , SIRARD, Jean-Claude , CARNOY, Christophe , FOUGERON, Delphine , CHABALGOITY, Jose Alejandro , MUÑOZ, Natalia
IPC分类号： A61K38/16 , A61K45/06 , A61K31/43 , A61K31/505 , A61K31/635 , A61K31/04
CPC分类号： A61K38/164 , A61K31/42 , A61K31/43 , A61K31/505 , A61K31/635 , A61K45/06 , Y02A50/402 , Y02A50/475 , Y02A50/481 , A61K2300/00
摘要： The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates to a Toll-like receptor (TLR) agonist for use in a method for the treatment of a bacterial infection in a subject in need thereof wherein the TLR agonist is administered to the subject in combination with at least one antibiotic.
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公开(公告)号：EP3632458A1
公开(公告)日：2020-04-08
申请号：EP19207885.5
申请日：2014-07-25
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , Institut fur Biomedizinische Technik der Universitat und ETH Zurich , Institut Pasteur De Lille , Université de Lille , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Universidad de la Republica Oriental del Uruguay
发明人： SIRARD, Jean-Claude , CHABALGOITY, Jose Alejandro , HARDT, Wolf-Dietrich , KAISER, Patrick , CARNOY, Christophe , FOUGERON, Delphine , MUNOZ, Natalia
IPC分类号： A61K38/16 , A61K45/06 , A61K31/43 , A61K31/505 , A61K31/635 , A61P31/04
摘要： The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates to a Toll-like receptor (TLR) agonist for use in a method for the treatment of a bacterial infection in a subject in need thereof wherein the TLR agonist is administered to the subject in combination with at least one antibiotic.
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5.发明授权
公开(公告)号：EP3236988B8
公开(公告)日：2020-08-19
申请号：EP15817338.5
申请日：2015-12-22
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