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1.发明公开JOINT PRODUCT CONTAINING PHENTERMINE AND TOPIRAMATE AND PREPARATION METHOD THEREFOR 有权随着产品芬特明和托吡酯及其制造方法CONNECTION
公开(公告)号：EP2829266A4
公开(公告)日：2015-11-11
申请号：EP13763543
申请日：2013-03-20
发明人： LI SONG , GAO CHUNSHENG , ZHONG WU , WANG YULI , YANG MEIYAN , SHAN LI , ZHOU XINBO , ZHENG ZHIBING , WANG XIAOKUI
CPC分类号： A61K31/357 , A61K9/4808 , A61K9/5047 , A61K9/5078 , A61K9/5084 , A61K9/5089 , A61K31/137 , A61K2300/00
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2.发明公开TOPIRAMATE SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 审中-公开具有延迟释放的药物头痛眼组合物，其制备方法及其用途
公开(公告)号：EP2829267A4
公开(公告)日：2015-09-30
申请号：EP13763714
申请日：2013-03-07
发明人： LI SONG , GAO CHUNSHENG , ZHONG WU , WANG YULI , YANG MEIYAN , SHAN LI , ZHOU XINBO , ZHENG ZHIBING , WANG XIAOKUI
IPC分类号： A61K9/22 , A61K31/7048 , A61K47/32 , A61K47/38 , A61P3/10 , A61P9/12 , A61P25/00 , A61P25/06 , A61P25/08 , A61P25/18 , A61P25/24
CPC分类号： A61K31/357 , A61K9/1676 , A61K9/5026 , A61K9/5042 , A61K9/5078 , A61K9/5089 , A61K31/7048
摘要： A sustained-release pharmaceutical composition of topiramate, which is free of binding agent. The sustained-release pharmaceutical composition of topiramate is a sustained-release pellet, comprising a blank pellet core, a drug layer, and a sustained-release coating layer.
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3.发明公开JOINT PRODUCT CONTAINING SYNEPHRINE AND TOPIRAMATE 审中-公开VERBINDUNGSPRODUKT MIT SYNEPHRIN UND TOPIRAMAT
公开(公告)号：EP2829270A4
公开(公告)日：2015-09-23
申请号：EP13764754
申请日：2013-03-22
发明人： LI SONG , GAO CHUNSHENG , ZHONG WU , WANG YULI , YANG MEIYAN , SHAN LI , ZHOU XINBO , ZHENG ZHIBING , WANG XIAOKUI
IPC分类号： A61K31/357 , A61K9/16 , A61K9/30 , A61K9/50 , A61K31/137 , A61P3/04
CPC分类号： A61K31/357 , A61K9/1635 , A61K9/1652 , A61K9/1676 , A61K9/5026 , A61K9/5047 , A61K9/5078 , A61K9/5084 , A61K9/5089 , A61K31/137 , A61K31/7048 , A61K45/06 , A61K2300/00
摘要： The present invention provides a joint product comprising synephrine and topiramate, in which the synephrine or salt thereof is administered in form of rapid-release preparation, preferably rapid-release pellet, having daily dose of 2mg to 25mg, preferably 5mg to 20mg; the topiramate is administered in form of sustained-release or controlled-release preparation, preferably sustained-release pellet, having daily dose of 20mg to 100mg, preferably 23mg to 92mg. The composition is used for treatment of obesity or other diseases associated with obesity.
摘要翻译： 本发明提供了包含昔萘福芬和托吡酯的联合产品，其中以每日剂量为2mg至25mg，优选5mg至20mg的快速释放制剂，优选快速释放丸剂的形式施用昔萘福林或其盐; 托吡酯以持续释放或控释制剂的形式施用，优选缓释丸剂，其日剂量为20mg至100mg，优选为23mg至92mg。 该组合物用于治疗与肥胖相关的肥胖或其它疾病。
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