专利检索 ap:("INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" OR "SOCIETE CIVILE BIOPROJET") AND inv:"ARRANG, Jean-Michel 160 avenue du Général-Leclerc" 第 1 页

1.

发明授权
COMPOSES AGONISTES DU RECEPTEUR H3 DE L'HISTAMINE A USAGE THERAPEUTIQUE, COMPOSITIONS PHARMACEUTIQUES AGISSANT COMME AGONISTES DUDIT RECEPTEUR ET PROCEDE DE PREPARATION 失效
标题翻译：组胺H3受体激动剂对于治疗用途，药物制剂H3受体激动性的工作，他们介绍联合国的方法

公开(公告)号：EP0482183B1

公开(公告)日：1997-07-30

申请号：EP91910312.7

申请日：1991-05-10

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , SOCIETE CIVILE BIOPROJET

发明人： GARBARG, Monique , ARRANG, Jean-Michel 160 avenue du Général-Leclerc , SCHUNACK, Walter , LIPP, Ralph , STARK, Holger , LECOMTE, Jeanne-Marie , SCHWARTZ, Jean-Charles

IPC分类号： C07D233/54 , A61K31/415

CPC分类号： C07D233/64

摘要： The compounds are derived from an R-NH2 amine with a strong affinity for the histamine H3-receptor and to the primary amine function of which is bonded a group forming a bond which can hydrolyze slowly in a neutral medium. The pharmaceutical compositions consist of these compounds and a pharmaceutically acceptable excipient. The compounds are used to produce a drug inhibiting histamine synthesis and release, and having, in particular, sedative, sleep regulating, anti-convulsive, anti-depressive, anti-allergic anti-inflammatory, anti-secretory or anti-ulcerous effects.