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1.发明授权DC-SIGN BLOCKERS AND THEIR USE FOR PREVENTING OR TREATING VIRAL INFECTIONS. 有权DC-SIGN受体阻滞剂和它们用于病毒感染的预防和治疗
公开(公告)号：EP1562628B1
公开(公告)日：2009-04-15
申请号：EP03810566.4
申请日：2003-11-05
CPC分类号： G01N33/566 , A61K38/162 , A61K2039/505 , C07K16/2851 , C07K16/2896 , G01N33/6872 , G01N2333/70596 , G01N2500/00 , G01N2500/10 , Y02A50/386 , Y02A50/53
摘要： The present invention relates to methods and compositions for preventing or treating diseases of a mammal, including viral infections, wherein at least one symptom of the disease is mediated at least in part by the binding of an effector molecule to a DC-SIGN receptor present on cells of the mammal to be treated. The invention also provides methods of identifying compositions, wherein the compositions are useful for treating mammalian diseases, including viral infections, for which at least one symptom of the disease is mediated at least in part by the specific binding of an effector molecule to a DC-SIGN receptor present on the cells that express the DC-SIGN receptor, belonging to the mammal to be treated. The invention further relates to compositions and methods for targeting subject molecules to cells that express the DC-SIGN receptor.
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2.发明公开UTILISATION D'UNE CHEMOKINE (SDF-1) LIGAND POUR LE RECEPTEUR DE LESTR/FUSIN/CXCR4 POUR PREVENIR OU TRAITER L'INFECTION PAR DES VIRUS DE TYPE VIH 失效使用LIGANDDEN受体LESTR /融合素/ CXCR4，趋化因子SDF-1感染艾滋病毒预防或治疗
公开(公告)号：EP0917575A1
公开(公告)日：1999-05-26
申请号：EP97935637.0
申请日：1997-07-25
申请人： INSTITUT PASTEUR
发明人： ARENZANA-SEISDEDOS, Fernando , VIRELIZIER, Jean-Louis , BAGGIOLINI, Marco , MOSER, Bernhard , CLARK-LEWIS, Ian
CPC分类号： C07K14/522 , A61K38/00 , A61K48/00 , C12N2799/021
摘要： An SDF-1 chemokine or a molecule derived therform for treating and/or preventing HIV retroviral infection is disclosed. Said chemokine consists of, is contained in or contains the following aminoacid sequence: KPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALN.
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3.发明公开DC-SIGN BLOCKERS AND THEIR USE FOR PREVENTING OR TREATING VIRAL INFECTIONS. 有权DC-SIGN受体阻滞剂和它们用于病毒感染的预防和治疗
公开(公告)号：EP1562628A1
公开(公告)日：2005-08-17
申请号：EP03810566.4
申请日：2003-11-05
CPC分类号： G01N33/566 , A61K38/162 , A61K2039/505 , C07K16/2851 , C07K16/2896 , G01N33/6872 , G01N2333/70596 , G01N2500/00 , G01N2500/10 , Y02A50/386 , Y02A50/53
摘要： The present invention relates to methods and compositions for preventing or treating diseases of a mammal, including viral infections, wherein at least one symptom of the disease is mediated at least in part by the binding of an effector molecule to a DC-SIGN receptor present on cells of the mammal to be treated. The invention also provides methods of identifying compositions, wherein the compositions are useful for treating mammalian diseases, including viral infections, for which at least one symptom of the disease is mediated at least in part by the specific binding of an effector molecule to a DC-SIGN receptor present on the cells that express the DC-SIGN receptor, belonging to the mammal to be treated. The invention further relates to compositions and methods for targeting subject molecules to cells that express the DC-SIGN receptor.
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4.发明公开
公开(公告)号：EP0953051A1
公开(公告)日：1999-11-03
申请号：EP97925120.0
申请日：1997-05-22
申请人： INSTITUT PASTEUR
发明人： ARENZANA-SEISDEDOS, Fernando , VIRELIZIER, Jean-Louis , BACHELERIE, Françoise , BAGGIOLINI, Marco , CLARK-LEWIS, Ian
CPC分类号： C07K14/523 , A61K38/00 , A61K48/00 , C07K14/52
摘要： The invention discloses the use of an antagonist compound (designated 'antagonist') of one or several molecules of the chemokine family for preparing a medicine for the prevention or the treatment of a viral infection.
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