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1.发明公开LIVE ATTENUATED BORDETELLA STRAINS AS A SINGLE DOSE VACCINE AGAINST WHOOPING COUGH 审中-公开LEBENDEABGESCHWÄCHTEBORDETELLASTÄMMEALS EINZELDOSISIMPFSTOFF GEGEN KEUCHHUSTEN
公开(公告)号：EP3045529A1
公开(公告)日：2016-07-20
申请号：EP16155296.3
申请日：2007-03-07
摘要： A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.
摘要翻译： 提供了至少包含突变的ptx基因，缺失或突变的dnt基因和异源ampG基因的突变的博德氏菌菌株。 减毒的突变型博德特氏菌属菌株可用于免疫原性组合物或用于治疗或预防博德氏杆菌感染的疫苗。 还提供了减毒的博德特氏菌属菌株用于制造疫苗或免疫原性组合物的用途，以及用于保护哺乳动物免受博德特氏菌感染的方法。
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公开(公告)号：EP3045529B1
公开(公告)日：2020-07-29
申请号：EP16155296.3
申请日：2007-03-07
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3.发明授权LIVE ATTENUATED BORDETELLA STRAINS AS A SINGLE DOSE VACCINE AGAINST WHOOPING COUGH 有权活的减毒百日咳菌单次剂量百日咳疫苗
公开(公告)号：EP1994139B1
公开(公告)日：2016-07-13
申请号：EP07711815.6
申请日：2007-03-07
CPC分类号： A61K39/099 , A61K2039/522 , A61K2039/523 , A61K2039/543
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4.发明公开LIVE ATTENUATED BORDETELLA STRAINS AS A SINGLE DOSE VACCINE AGAINST WHOOPING COUGH 有权活的减毒百日咳菌单次剂量百日咳疫苗
公开(公告)号：EP1994139A1
公开(公告)日：2008-11-26
申请号：EP07711815.6
申请日：2007-03-07
CPC分类号： A61K39/099 , A61K2039/522 , A61K2039/523 , A61K2039/543
摘要： A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.
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公开(公告)号：EP3697439A1
公开(公告)日：2020-08-26
申请号：EP18815945.3
申请日：2018-10-18
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公开(公告)号：EP3800244A1
公开(公告)日：2021-04-07
申请号：EP20183971.9
申请日：2007-03-07
摘要： A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.
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