公开(公告)号：EP4050004A1

公开(公告)日：2022-08-31

申请号：EP20892802.8

申请日：2020-09-15

申请人： INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES ,  Changchun Intellicrown Pharmaceutical Co., Ltd.

发明人： WU, Song ,  SUN, Hua ,  ZHANG, Jinlan ,  ZHANG, Wenxuan ,  WANG, Zhe ,  YANG, Qingyun ,  JIANG, Lin ,  CHEN, Zihan ,  SHEN, Jing ,  ZHANG, Jie ,  ZHANG, Chi ,  HAN, Zunsheng ,  QIN, Tong ,  ZHANG, Yuanyuan

IPC分类号： C07D317/68 ,  A61K31/5377 ,  A61P1/16 ,  A61P31/14 ,  A61P31/20 ,  A61P37/02

摘要： The invention relates to the field of pharmaceutical chemistry, and it particularly relates to a left-handed bicyclic morpholine and a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition and use thereof in the preparation of medicaments for preventing and/or treating liver diseases and the like.