专利检索 ap:("IRBM S.P.A." OR "C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening") AND inv:"QUOTADAMO, Antonio" 第 1 页

1.

发明公开
FLAVIVIRUS INHIBITORS 审中-公开

公开(公告)号：EP4282862A1

公开(公告)日：2023-11-29

申请号：EP22175308.0

申请日：2022-05-25

申请人： IRBM S.P.A. , C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening

发明人： ALLI, Cristina , BRESCIANI, Alberto , DI FABIO, Romano , MONTALBETTI, Christian A.G.N. , ONTORIA ONTORIA, Jesus Maria , PAONESSA, Giacomo , QUOTADAMO, Antonio , TORRENTE DE HARO, Esther , BENCHEVA, Leda , AMAUDRUT, Jerome

IPC分类号： C07D271/04 , A61P31/14

摘要： The invention relates to compounds that are inhibitors of Flavivirus NS2B-NS3 proteases and inhibit replication of flavivirus in cells. Compounds of this invention are useful alone or in combination with other agents for use in the treatment of infections caused by Flaviviruses, in particular by Dengue, West Nile, Zika, Japan Encephalitis viruses.