公开(公告)号：EP3741762A1

公开(公告)日：2020-11-25

申请号：EP19176238.4

申请日：2019-05-23

申请人： IRBM S.P.A. ,  Promidis S.r.l. ,  Ospedale San Raffaele S.r.l. ,  Istituto Nazionale Di Genetica Molecolare-INGM

发明人： De Francesco, Raffaele ,  Donnici, Lorena ,  Di Fabio, Romano ,  Summa, Vincenzo ,  Guidotti, Luca ,  Iannacone, Matteo ,  Bencheva, Leda Ivanova ,  De Matteo, Marilenia ,  Ferrante, Luca ,  Prandi, Adolfo ,  Randazzo, Pietro ,  Gornati, Davide ,  Grillo, Alessandro

IPC分类号： C07D513/14 ,  C07D515/14 ,  A61P31/20 ,  A61K31/407

摘要： The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.

公开(公告)号：EP3825318A1

公开(公告)日：2021-05-26

申请号：EP19211249.8

申请日：2019-11-25

申请人： Promidis S.r.l. ,  Ospedale San Raffaele S.r.l. ,  Istituto Nazionale di Genetica Molecolare - INGM ,  IRBM S.P.A.

发明人： De Francesco, Raffaele ,  Donnici, Lorena ,  Di Fabio, Romano ,  Summa, Vincenzo ,  Guidotti, Luca ,  Iannacone, Matteo ,  Bencheva, Leda Ivanova ,  De Matteo, Marilenia ,  Ferrante, Luca ,  Prandi, Adolfo ,  Randazzo, Pietro ,  Gornati, Davide ,  Grillo, Alessandro

IPC分类号： C07D515/14 ,  A61P31/20 ,  A61K31/407

摘要： The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.