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1.发明公开
公开(公告)号：EP3377624A1
公开(公告)日：2018-09-26
申请号：EP16798365.9
申请日：2016-11-10
发明人： OGER, Elodie , CHABERT, Rachel , IMBERT, Isabelle , BOTTO, Jean-Marie , DOMLOGE, Nouha , PERNODET, Nadine , DONG, Kelly , MANTELIN, Joel , CHEN, Chia-Wen
CPC分类号： C12N15/1003 , A61K8/606 , A61K8/9789 , A61Q19/00 , A61Q19/08 , C07H1/08 , C07H21/02 , C12N15/1017
摘要： The invention relates to a process for obtaining an aqueous extract enriched with small RNAs having a maximum length of 150 nucleotides from a plant material. The invention is characterized in that it comprises the following steps according to which: a) the plant material is placed in the presence of water; b) tetrasodium ethylenediaminetetraacetic acid (EDTA) is added to the mixture obtained in a) at a pH of between 10.5 and 11; c) the pH of the mixture obtained in b) is then adjusted to a value of between 6 and 8; d) the mixture obtained in c) is purified so as to remove the plant material and to recover a crude aqueous extract; and e) the pH is verified and is readjusted if necessary to a value of between 6 and 8. The invention also relates to an aqueous extract of plant material, enriched with small RNAs having a maximum length of 150 nucleotides, capable of being obtained by means of such a process, and also to the compositions comprising such an extract and to the cosmetic uses thereof for combatting the signs of skin ageing, and improving skin moisturization.
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2.发明公开METHOD OF COSMETIC TREATMENT TO PROTECT THE SKIN FROM POLLUTION AND IMPROVE SKIN REGENERATION 审中-公开化妆品处理保护皮肤免受污染和改善皮肤再生的方法
公开(公告)号：EP3280390A1
公开(公告)日：2018-02-14
申请号：EP16777056.9
申请日：2016-03-30
发明人： PORTOLAN, Frédérique , BOTTO, Jean-Marie , MANTELIN, Joel , IMBERT, Isabelle , DOMLOGE, Nouha , YAROSH, Daniel B. , JURUKOVSKA-KARAMAN, Nevena , PERNODET, Nadine , DONG, Kelly , PELLE, Edward
CPC分类号： A61K8/9794 , A61K8/9789 , A61K2800/5922 , A61Q19/00 , A61Q19/08
摘要： The present invention relates to the cosmetic use of a combination of a hydrolysed rice extract and a grapeseed extract as an active agent to protect cutaneous cells from pollution. The present invention relates also to a cosmetic method of treatment for protecting skin epidermal cells from atmospheric pollution comprising applying on the skin area to be treated a composition comprising a combination of a hydrolysed rice extract and a grapeseed extract.
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公开(公告)号：EP3166649A1
公开(公告)日：2017-05-17
申请号：EP15818322.8
申请日：2015-07-07
发明人： PORTOLAN, Frédérique , LEQUOY, Valerie , BOTTO, Jean-Marie , MANTELIN, Joel , IMBERT, Isabelle , DOMLOGE, Nouha , GARCIA, Noelle , PERNODET, Nadine A. , DONG, Kelly , PELLE, Edward , HANEY, Carl
IPC分类号： A61K125/00
CPC分类号： A61Q17/04 , A61K2800/85 , A61Q19/08
摘要： The invention relates to a Truffle extract for skin cosmetic use, comprising compounds having a molecular weight of less than 5 kDa. The invention also relates to a cosmetic method of treatment designed to reduce and/or correct the signs of aging and photo-aging of the skin and keratinous appendages, and to protect the skin against aggressions due to ultraviolet radiation.
摘要翻译： 本发明涉及用于皮肤化妆品用途的松露提取物，其包含分子量小于5kDa的化合物。 本发明还涉及设计用于减少和/或校正皮肤和角质附件的老化和光老化迹象并且保护皮肤免受紫外线辐射侵袭的美容治疗方法。
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4.发明公开METHOD AND COMPOSITIONS FOR IMPROVING SELECTIVE CATABOLYSIS IN CELLS OF KERATIN SURFACES 审中-公开方法和组合物改善的选择性KATABOLYSE在KERATINOBERFLÄCHEN的细胞
公开(公告)号：EP2897582A1
公开(公告)日：2015-07-29
申请号：EP13836647.1
申请日：2013-09-09
申请人： ELC Management LLC
CPC分类号： A61K8/99 , A61K8/733 , A61K2800/78 , A61Q19/00 , A61Q19/08
摘要： A skin care composition for stimulating selective catabolysis in cells of keratin surfaces comprising at least one autophagy activator and at least one proteasome activator, and a method for improving selective catabolysis in cells of keratin surfaces by treating with the composition.
摘要翻译： 在角蛋白表面包括至少一个自噬活化剂和至少一种蛋白酶活化剂，并且通过用所述组合物处理用于在角蛋白表面的细胞的选择性改善catabolysis的方法的细胞刺激选择性catabolysis的护肤组合物。
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公开(公告)号：EP2897582B1
公开(公告)日：2018-12-05
申请号：EP13836647.1
申请日：2013-09-09
申请人： ELC Management LLC
CPC分类号： A61K8/99 , A61K8/733 , A61K2800/78 , A61Q19/00 , A61Q19/08
摘要： A skin care composition for stimulating selective catabolysis in cells of keratin surfaces comprising at least one autophagy activator and at least one proteasome activator, and a method for improving selective catabolysis in cells of keratin surfaces by treating with the composition.
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6.发明公开
公开(公告)号：EP3229825A1
公开(公告)日：2017-10-18
申请号：EP15868488.6
申请日：2015-11-23
申请人： ELC Management LLC
发明人： PERNODET, Nadine , DONG, Kelly , PELLE, Edward
摘要： Compositions of the invention comprise 8-oxoguanine glycosylase (OGG1) and SIRT6 activating peptide G-A-G-V-S-A-E-NH2. Compositions of the invention exhibit anti-aging effects by promoting the repair of skin cell DNA and/or by protecting skin cell DNA from UV damage.
摘要翻译： 本发明的组合物包含8-羟基鸟嘌呤糖基化酶（OGG1）和SIRT6激活肽G-A-G-V-S-A-E-NH2。本发明的组合物通过促进皮肤细胞DNA的修复和/或通过保护皮肤细胞DNA免受紫外线损伤而表现出抗衰老作用。
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7.发明公开
公开(公告)号：EP4039254A1
公开(公告)日：2022-08-10
申请号：EP21211157.9
申请日：2018-03-06
申请人： ELC Management LLC , Symrise AG
发明人： PERNODET, Nadine , CHEN, Chia-Wen , DONG, Kelly , HUANG, Jingyu , KOCH, Oskar , BUGDAHN, Nikolas
IPC分类号： A61K31/192 , A61K8/37 , A61K8/02 , A61P17/00 , A61Q17/04 , A61Q19/00 , A61K9/00 , A61K9/107 , A61K31/216 , A61Q19/08 , A61K8/06
摘要： The invention provides a topical composition comprising a synthetic ester of sinapinic acid. The invention also provides a method for synthesizing sinapoyl malate.
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8.发明公开
公开(公告)号：EP3592341A1
公开(公告)日：2020-01-15
申请号：EP18764435.6
申请日：2018-03-06
申请人： ELC Management LLC , Symrise AG
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公开(公告)号：EP3229825B1
公开(公告)日：2020-01-08
申请号：EP15868488.6
申请日：2015-11-23
申请人： ELC Management LLC
发明人： PERNODET, Nadine , DONG, Kelly , PELLE, Edward
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