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    CRYSTALLINE FORMS
    1.
    发明公开
    CRYSTALLINE FORMS 审中-公开

    公开(公告)号：EP3981774A1

    公开(公告)日：2022-04-13

    申请号：EP21206477.8

    申请日：2017-09-21

    申请人： Idorsia Pharmaceuticals Ltd

    发明人： LEUENBERGER, Daniel ,  REBER, Stefan ,  VON RAUMER, Markus

    IPC分类号： C07F9/6558 ,  A61K31/675 ,  A61P9/00 ,  A61P9/10 ,  A61P27/02

    摘要： The invention relates to crystalline forms of 4-((R)-2-{[6-((S)-3-methoxy-pyrrolidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-3-phosphono-propionyl)-piperazine-1-carboxylic acid butyl ester hydrochloride, processes for the preparation thereof, pharmaceutical compositions comprising said crystalline forms, pharmaceutical compositions prepared from such crystalline forms and their use as a medicament, especially as a P2Y 12 receptor antagonist.