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公开(公告)号：EP2956774A1
公开(公告)日：2015-12-23
申请号：EP14707114.6
申请日：2014-02-17
申请人： Imabiotech , Université des Sciences et Technologies De Lille - Lille 1 , Centre National de la Recherche Scientifique (C.N.R.S.)
CPC分类号： G01N33/58 , G01N33/6848 , G01N2560/00 , H01J49/00 , H01J49/0027 , H01J49/164 , H01J49/40
摘要： The present invention relates to the field of the detection of molecules of interest in a sample, preferably by mass spectrometry. The present invention concerns a label compound, a molecule labeled with said compound (a conjugate), a method of detection of a molecule of interest (a target molecule) in a sample involving said conjugate, a kit to implement said method and a process for the preparation of the label.
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2.发明公开MULTIMERIC COMPOUNDS OF A KRINGLE DOMAIN FROM THE HEPATOCYTE GROWTH FACTOR / SCATTER FACTOR (HGF/SF) 审中-公开来自肝细胞生长因子/散发因子（HGF / SF）的KRINGLE结构域的多元化合物
公开(公告)号：EP3253782A1
公开(公告)日：2017-12-13
申请号：EP16701313.5
申请日：2016-01-21
申请人： Université des Sciences et Technologies De Lille - Lille 1 , Centre National de la Recherche Scientifique , Institut Pasteur de Lille , Université de Lille 2 Droit et Santé , Universita' Degli Studi Di Pavia
发明人： VICOGNE, Jerome , MELNYK, Oleg , OLLIVIER, Nathalie , ADRIAENSSENS, Eric , LECLERCQ, Berenice , SIMONNEAU, Claire , DE NOLA, Giovanni , GHERARDI, Ermanno , DE JONGE, Hugo
IPC分类号： C07K14/475 , A61K38/00 , G01N33/74
CPC分类号： A61K47/665 , A61K38/00 , A61K38/1833 , A61K47/557 , A61K49/0002 , C07K14/4753 , G01N33/502 , G01N33/5023 , G01N33/582
摘要： Disclosed are multimeric compounds of K1 domains from the Hepatocyte Growth Factor/Scatter Factor (HGF/SF) being able to induce activation of the tyrosine kinase receptor MET and their uses.
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公开(公告)号：EP3247719A1
公开(公告)日：2017-11-29
申请号：EP16701312.7
申请日：2016-01-21
申请人： Université des Sciences et Technologies De Lille - Lille 1 , Centre National de la Recherche Scientifique , Institut Pasteur de Lille , Université de Lille 2 Droit et Santé , Universita' Degli Studi Di Pavia
发明人： VICOGNE, Jerome , MELNYK, Oleg , OLLIVIER, Nathalie , ADRIAENSSENS, Eric , LECLERCQ, Berenice , SIMONNEAU, Claire , DE NOLA, Giovanni , GHERARDI, Ermanno , DE JONGE, Hugo
IPC分类号： C07K14/475 , A61K38/00 , C12N15/63 , G01N33/74
CPC分类号： C07K14/4753 , A61K38/00 , C12N15/63
摘要： Disclosed are proteins derived from the HGF/SF which are able to induce activation of the tyrosine kinase receptor MET and their uses, in particular to promote tissue regeneration. Further disclosed are nucleic acid molecules coding such protein, expression vectors containing such nucleic acid molecule, host cells containing such expression vectors, and related compositions.
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公开(公告)号：EP2768842B1
公开(公告)日：2018-07-25
申请号：EP12772951.5
申请日：2012-10-16
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