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公开(公告)号:EP2081594B1
公开(公告)日:2014-10-22
申请号:EP07819171.5
申请日:2007-10-19
申请人: ImevaX GmbH
IPC分类号: A61K39/106 , G01N33/50 , A61K38/00 , C12N9/10
CPC分类号: A61K39/105 , A61K39/00 , C07K16/121 , C07K16/40 , C12N9/104 , C12Q1/48 , C12Y203/02002 , G01N2333/91074 , Y02A50/472
摘要: Use of a ligand of the gamma-glutamyl transpeptldase of H. pylori (HPGGT) for the manufacture of a drug for the treatment of H. pylori infections, in particular gastro duodenal disorders, whereas the ligand significantly inhibits the HPGGT activity and abrogates the HPGGT dependent suppression of lymphocyte proliferation as assessed in a lymphocyte proliferation assay.