公开(公告)号：EP1265998A2

公开(公告)日：2002-12-18

申请号：EP01913041.8

申请日：2001-02-21

申请人： Incyte Genomics, Inc.

发明人： PANZER, Scott ,  SPIRO, Peter A. ,  BANVILLE, Steven C. ,  SHAH, Purvi ,  CHALUP, Michael S. ,  CHANG, Simon C. ,  CHEN, Alice ,  D'SA, Steven A. ,  AMSHEY, Stefan ,  DAHL, Christopher R. ,  DAM, Tam C. ,  DANIELS, Susan E. ,  DUFOUR, Gerard E. ,  FLORES, Vincent ,  FONG, Willy T. ,  GREENAWALT, Lila B. ,  HILLMAN, Jennifer L. ,  JONES, Anissa L. ,  LIU, Tommy F. ,  ROSEBERRY, Ann M. ,  ROSEN, Bruce H. ,  RUSSO, Frank D. ,  STOCKDREHER, Theresa K. ,  DAFFO, Abel ,  WRIGHT, Rachel J. ,  YAP, Pierre E. ,  YU, Jimmy Y. ,  BRADLEY, Diana L. ,  BRATCHER, Shawn R. ,  CHEN, Wensheng ,  COHEN, Howard J. ,  HODGSON, David M. ,  LINCOLN, Stephen E. ,  JACKSON, Stuart

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/18 ,  A61K38/17 ,  A01K67/027 ,  G01N33/50 ,  G01N33/68 ,  C12Q1/68

摘要： The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.

公开(公告)号：EP1263949A2

公开(公告)日：2002-12-11

申请号：EP01908799.8

申请日：2001-02-01

申请人： Incyte Genomics, Inc.

发明人： PANZER, Scott ,  SPIRO, Peter A. ,  BANVILLE, Steven C. ,  SHAH, Purvi ,  CHALUP, Michael S. ,  CHANG, Simon C. ,  CHEN, Alice ,  D'SA, Steven A. ,  AMSHEY, Stefan R. ,  DAHL, Christopher R. ,  DAM, Tam C. ,  DANIELS, Susan E. ,  DUFOUR, Gerard E. ,  FLORES, Vincent ,  FONG, Willy T. ,  GREENAWALT, Lila B. ,  HILLMAN, Jennifer L. ,  JONES, Anissa L. ,  LIU, Tommy F. ,  ROSEBERRY, Ann M. ,  ROSEN, Bruce H. ,  RUSSO, Frank D. ,  STOCKDREHER, Theresa K. ,  DAFFO, Abel ,  WRIGHT, Rachel J. ,  YAP, Pierre E. ,  YU, Jimmy Y. ,  BRADLEY, Diana L. ,  BRATCHER, Shawn R. ,  CHEN, Wensheng ,  COHEN, Howard J. ,  HODGSON, David M. ,  LINCOLN, Stephen E.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/18 ,  A61K38/17 ,  A01K67/027 ,  G01N33/68 ,  G01N33/50 ,  C12Q1/68

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00

摘要： The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.