专利检索 ap:("Incyte Holdings Corporation") AND inv:"Combs, Andrew P." 第 1 页

1.

发明授权
pyrrolo[2,3-b]pyridin-4-yl-amines and pyrrolo[2m3-b]pyrimidin-4-yl-amines as janus kinase inhibitors 有权
标题翻译：吡咯并[2,3-b]吡啶-4-基 - 胺和吡咯并[2m 3-b]嘧啶-4-基 - 胺作为janus激酶抑制剂

公开(公告)号：EP2671882B1

公开(公告)日：2018-02-21

申请号：EP13171524.5

申请日：2005-12-21

申请人： Incyte Holdings Corporation

发明人： Rodgers, James D. , Wang, Heisheng , Combs, Andrew P. , Sparks, Richard B.

IPC分类号： C07D471/04 , C07D491/04 , C07D498/08 , C07D513/02 , C07D515/02 , A01N43/42 , A61K31/44 , C07D487/04

CPC分类号： C07D471/04 , C07D487/04

摘要： The present invention provides pyrrolo[2,3-b]pyridine-4-yl-amines pyrrolo[2m3-b]pyrimidin-4-yl-amines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases and cancer.

2.

发明授权
Modulators of indoleamine 2,3-dioxygenase and methods of using the same 有权
标题翻译：吲哚胺2,3-双加氧酶及其方法中使用的调制器

公开(公告)号：EP2559690B1

公开(公告)日：2016-03-30

申请号：EP12178315.3

申请日：2006-05-09

申请人： Incyte Holdings Corporation

发明人： Combs, Andrew P. , Yue, Eddy W.

IPC分类号： C07D271/08 , C07D413/12 , C07D413/14 , A61K31/4245 , A61P35/00 , A61K45/06 , A61K31/433 , A61K31/5377 , A61K31/541 , C07D285/10 , C07D417/12 , C07D417/14

CPC分类号： C07D271/08 , A61K31/4245 , A61K31/433 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D285/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14

摘要： The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof.