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1.发明公开Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes 审中-公开噻唑烷二酮亚苄基及其类似物及其对糖尿病的治疗
公开(公告)号：EP1593677A3
公开(公告)日：2006-01-04
申请号：EP05017383.0
申请日：2000-08-31
发明人： Pfahl, Magnus , Tachdjian, Catherine , Al-Shamma, Hussien A. , Fanjul, Andrea , Pleynet, David P. M. , Spruce, Lyle W.
IPC分类号： C07D277/34 , C07D277/36 , C07D417/06 , C07D417/10 , C07D233/42 , C07D233/96 , C07D233/40 , C07D401/06 , C07D403/10 , C07D401/10 , C07D405/10 , C07D261/12 , A61K31/4166 , A61K31/426 , A61K31/42 , A61K31/4439 , A61P3/10
CPC分类号： C07D233/86 , C07D233/78 , C07D233/96 , C07D277/34 , C07D277/36 , C07D401/06 , C07D401/10 , C07D405/10 , C07D417/06 , C07D417/10
摘要： The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatiod arthritis, Crohn's Disease or Inflammatory Bowel Disease.
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2.发明公开Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes 审中-公开苄基噻唑烷二酮和分析和维他命Zur Behandlung von糖尿病
公开(公告)号：EP1593677A2
公开(公告)日：2005-11-09
申请号：EP05017383.0
申请日：2000-08-31
发明人： Pfahl, Magnus , Tachdjian, Catherine , Al-Shamma, Hussien A. , Fanjul, Andrea , Pleynet, David P. M. , Spruce, Lyle W.
IPC分类号： C07D277/34 , C07D277/36 , C07D417/06 , C07D417/10 , C07D233/42 , C07D233/96 , C07D233/40 , C07D401/06 , C07D403/10 , C07D401/10 , C07D405/10 , C07D261/12 , A61K31/4166 , A61K31/426 , A61K31/42 , A61K31/4439 , A61P3/10
CPC分类号： C07D233/86 , C07D233/78 , C07D233/96 , C07D277/34 , C07D277/36 , C07D401/06 , C07D401/10 , C07D405/10 , C07D417/06 , C07D417/10
摘要： The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatiod arthritis, Crohn's Disease or Inflammatory Bowel Disease.
摘要翻译： 本发明涉及可用于治疗与脂质和碳水化合物代谢有关的疾病的某些取代的式（I）的杂环，例如2型糖尿病，脂肪细胞分化，不受控制的增殖，例如淋巴瘤，霍奇金病，白血病，乳腺癌 一般癌症，前列腺癌或癌症; 和炎症，如骨关节炎，风湿性关节炎，克罗恩病或炎症性肠病。
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