COMPOSITION COMPRISING POLYSACCHARIDES EXTRACTED FROM LENTINUS, PORIA AND TREMELLA AND USE THEREOF FOR COMBATING INFLUENZA VIRUS
    4.
    发明公开
    COMPOSITION COMPRISING POLYSACCHARIDES EXTRACTED FROM LENTINUS, PORIA AND TREMELLA AND USE THEREOF FOR COMBATING INFLUENZA VIRUS 审中-公开
    含有多糖的多糖组合物及其用于治疗流感病毒的组合物

    公开(公告)号:EP3216454A1

    公开(公告)日:2017-09-13

    申请号:EP16177331.2

    申请日:2016-06-30

    IPC分类号: A61K31/715 A61P31/16

    摘要: The present invention relates to the field of food or health care product, in particular a polysaccharide composition and use thereof. In the present invention, lentinan, pachymaran and tremellan are compounded. The resultant composition can significantly improve the survival rate and quality of life of mice infected by influenza virus, improve the pulmonary inflammatory lesion degree in mice infected by influenza virus, significantly improve levels of specific antibodies in serum of mice infected by influenza virus, significantly decrease the virus content in the lung of mice infected by influenza virus, as well as improve levels of cytokines IL-2 and IL-5 in the lung. In comparison with existing vaccines or single polysaccharides, the polysaccharide composition as provided in the present invention has more significant protective effects on mice infected by influenza virus.

    摘要翻译: 本发明涉及食品或保健产品领域,特别是多糖组合物及其用途。 在本发明中,复合了香菇多糖,厚朴多糖和银耳多糖。 所得组合物可显着提高流感病毒感染小鼠的存活率和生活质量,改善流感病毒感染小鼠的肺部炎症病变程度,显着提高流感病毒感染小鼠血清中特异性抗体水平,显着降低 感染流感病毒的小鼠的肺中的病毒含量,以及提高肺中细胞因子IL-2和IL-5的水平。 与现有疫苗或单一多糖相比,本发明提供的多糖组合物对流感病毒感染的小鼠具有更显着的保护作用。

    A BONE AND JOINT PROTECTION COMPOSITION AND USE THEREOF
    5.
    发明公开
    A BONE AND JOINT PROTECTION COMPOSITION AND USE THEREOF 审中-公开
    KENCHEN- UND GELENKSCHUTZZUSAMMENSETZUNG UND VERWENDUNG DAVON

    公开(公告)号:EP3117834A1

    公开(公告)日:2017-01-18

    申请号:EP16179138.9

    申请日:2016-07-13

    摘要: The invention relates to the pharmaceutical field, in particular to a bone and joint protection composition and use thereof. According to the composition, the four Chinese medicinal herbs Eucommiae Cortex, Achyranthis Bidentatae Radix, Astragali Radix and Chuanxiong Rhizoma are used in cooperation, and the effects of enhancing the bone density, preventing and/or relieving osteoporosis, restraining the activity of osteoclast, promoting the function of bone cells, increasing the formation of calcified bone, promoting cartilage repair, delaying joint recession and repairing joint damage are achieved through multiple approaches and multiple levels. On the basis, by adding glucosamine hydrochloride, chondroitin sulfate and/or collagen, the bone density can be obviously enhanced, the osteoporosis can be prevented and/or treated; the activity of the osteoclast can be obviously restrained, the function of bone cells can be promoted, the formation of calcified bone can be increased, the cartilage repair can be promoted, joint recession can be delayed, and the joint damage can be repaired.

    摘要翻译: 本发明涉及药物领域,特别涉及骨骼和关节保护组合物及其用途。 根据组成,合作使用四种中药杜仲皮,Achyranthis Bidentatae Radix,黄芪和川g,并提高骨密度,预防和/或缓解骨质疏松症,抑制破骨细胞活性,促进作用 通过多种方法和多层次实现骨细胞功能,增加钙化骨形成,促进软骨修复,延缓关节衰退和修复关节损伤。 在此基础上,通过加入盐酸氨基葡萄糖,硫酸软骨素和/或胶原蛋白,可明显提高骨密度,可预防和/或治疗骨质疏松症; 可明显抑制破骨细胞的活性,可促进骨细胞的功能,可增加钙化骨的形成,促进软骨修复,延缓关节衰退,并可修复关节损伤。