公开(公告)号：EP3177231A2

公开(公告)日：2017-06-14

申请号：EP15829185.6

申请日：2015-08-07

申请人： Insight Innovations LLC ,  Sharklet Technologies, Inc. ,  University of Florida Research Foundation, Inc.

发明人： CUEVAS, Kevin, H. ,  REDDY, Shravanthi, T. ,  MAGIN, Chelsea, Marie ,  METTETAL, Michael, R. ,  BRENNAN, Anthony, B. ,  MAY, Rhea, Marie ,  MANN, Ethan, Eugene

IPC分类号： A61F2/14

CPC分类号： A61M16/04 ,  A61F2/0077 ,  A61F2/1601 ,  A61F2002/009 ,  A61F2250/0026 ,  A61F2250/0051 ,  A61F2250/0056 ,  A61F2250/0068 ,  A61M25/00 ,  F16L9/12 ,  F28F1/00

摘要： Disclosed herein is an article including a path that extends across at least a portion of a surface of the article, the path being defined by at least one channel that traverses at least a portion of the surface or a first plurality of spaced features disposed on or in at least a portion of the surface; the spaced features arranged in a plurality of groupings; the groupings of features comprising repeat units; the spaced features within a grouping being spaced apart at an average distance of about 1 nanometer to about 500 micrometers to define a path that traverses the plurality of spaced features; each feature having a surface that is substantially parallel to a surface on a neighboring feature; each feature being separated from its neighboring feature; the groupings of features being arranged with respect to one another so as to define a tortuous pathway.

摘要翻译： 通常，眼内植入物具有在外表面上的多个图案表面元件，所述多个图案表面元件以间隔开的关系设置，限定适于控制流体流动或流体悬浮在流体中的曲折路径，或者抑制 细胞。 具体而言，植入眼内晶状体和眼后囊表面之间的眼内植入物通过提供结构障碍以减少眼后囊混浊，抑制白内障手术后残留晶状体上皮细胞的生长或迁移。微图案化眼内植入物