专利检索 ap:("Iqbal, Aman") AND inv:"Iqbal, Aman" 第 1 页

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发明公开
METHOD OF DEVELOPING SMALL MOLECULE PEPTIDE CONJUGATES FOR BIOMEDICAL APPLICATIONS 审中-公开
标题翻译：开发用于生物医学应用的小分子肽共轭物的方法

公开(公告)号：EP3247717A1

公开(公告)日：2017-11-29

申请号：EP16739853.6

申请日：2016-01-20

申请人： Iqbal, Aman

发明人： Iqbal, Aman

IPC分类号： C07K1/00 , G01N33/566

CPC分类号： G01N33/6845 , B01J19/0046 , B01J2219/00596 , B01J2219/00725 , C07K1/00 , C07K1/047 , C40B30/02 , C40B50/02 , G01N21/658 , G01N33/566 , G06F19/18

摘要： This application provides a platform design wherein a substrate peptide of the protein-protein interaction complex is tagged with a variety of small molecule fragments using amide chemistry. The method of hit discovery coupled with subsequent amide-mediated rapid diversification for lead generation reduces time and cost to discovery and development of target specific small molecule leads for the inhibition of protein-protein interactions.