公开(公告)号：EP1630157A4

公开(公告)日：2007-05-23

申请号：EP04735338

申请日：2004-05-28

申请人： JAPAN TOBACCO INC

发明人： SHINAGAWA YUKO ,  INOUE TERUHIKO ,  KIGUCHU TOSHIHIRO ,  IKENOGAMI TAKU ,  OGAWA NAOKI ,  NAKAGAWA TAKASHI ,  SHINDO MASANORI ,  SOEJIMA YUKI

IPC分类号： C07C217/28 ,  A61K31/165 ,  A61K31/195 ,  A61K31/216 ,  A61K31/255 ,  A61K31/265 ,  A61K31/381 ,  A61K31/41 ,  A61K31/4245 ,  A61K31/426 ,  A61P1/02 ,  A61P3/14 ,  A61P19/00 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07C233/22 ,  C07C235/42 ,  C07C259/10 ,  C07C311/51 ,  C07D257/04 ,  C07D271/06 ,  C07D277/32 ,  C07D277/56 ,  C07D285/08 ,  C07D333/38 ,  C07F9/38 ,  C07F9/40

CPC分类号： C07D257/04 ,  C07C217/28 ,  C07C311/51 ,  C07D277/56 ,  C07D285/08 ,  C07D333/38 ,  C07F9/3834 ,  C07F9/4021

摘要： A compound having a calcium-sensitive receptor antagonism; and a pharmaceutical composition comprising the compound. In particular, a calcium receptor antagonist; and a curative for osteoporosis. More specifically, a compound of the formula: (1) (wherein the characters have the same meaning as in the description) a pharmacologically acceptable salt thereof, or the same in optically active form.