公开(公告)号：EP0604656A4

公开(公告)日：1995-03-22

申请号：EP93910351

申请日：1993-05-18

申请人： JAPAN TOBACCO INC

发明人： MATSUMOTO KATSUYA JAPAN TOBACC ,  EBATA TAKASHI JAPAN TOBACCO IN ,  KOSEKI KOSHI JAPAN TOBACCO INC ,  OKANO KOJI JAPAN TOBACCO INC L ,  KAWAKAMI HIROSHI JAPAN TOBACCO ,  MATSUSHITA HAJIME JAPAN TOBACC

IPC分类号： C07D301/02 ,  C07D301/03 ,  C07D301/24 ,  C07D303/04 ,  C07D493/04 ,  C07D493/08 ,  C07D493/18 ,  C07H3/10 ,  C07D301/26

CPC分类号： C07D301/14 ,  C07D301/02 ,  C07D301/24 ,  C07D303/04 ,  C07D493/04 ,  C07D493/08 ,  C07H3/10

摘要： A process for producing an epoxide represented by general formula (1a) or (1b), which comprises reacting an olefin represented by general formula (2) with a compound containing iodine and an acyloxy ion and treating the reaction product under a basic condition so as to form an oxirane ring on the stereochemically crowded side of the feed olefin. In formulae (1a), (1b) and (2), R?1, R2, R3 and R4¿ represent each hydrogen, alkyl, alkenyl, aryl, alkoxy, aryloxy, acyl, alkoxycarbonyl, aryloxycarbonyl, aralkyl, silyl or silyloxy, provided that when each of these groups represents a divalent group, they may be combined together to represent a cyclic group, and that these groups may be the same or different from one another and further may be substituted or branched. The plane formed by the double bond, R?1, R2, R3 and R4¿ has one side which is stereochemically more crowded than the other side.

公开(公告)号：EP0603409A4

公开(公告)日：1995-02-22

申请号：EP93913535

申请日：1993-06-17

申请人： JAPAN TOBACCO INC

发明人： KUNO HIDEYUKI JAPAN TOBACCO IN ,  SHIBAGAKI MAKOTO JAPAN TOBACCO ,  TAKAHASHI KYOKO JAPAN TOBACCO ,  MATSUSHITA HAJIME JAPAN TOBACC

IPC分类号： B01J21/06 ,  B01J31/02 ,  B01J37/02 ,  C07C45/29 ,  C07C45/38 ,  C07C45/39 ,  C07D309/30 ,  C07B61/00

CPC分类号： B01J21/066 ,  B01J31/0274 ,  B01J37/0209 ,  B01J2231/70 ,  B01J2231/763 ,  C07C45/29 ,  C07C45/39 ,  C07D309/30 ,  C07C47/02 ,  C07C47/11 ,  C07C49/403

摘要： Hydrated zirconium oxide modified with an organo-silicon compound, wherein 50-90 % of the hydroxyl groups present on the surface of hydrated zirconium oxide are substituted by said compound. The modified oxide can be efficiently utilized in the oxidation of an alcohol into an aldehyde or ketone and in the production of a lactone.

摘要翻译： 用有机硅化合物改性的水合氧化锆，其中存在于水合氧化锆表面上的50-90％的羟基被所述化合物取代。 改性氧化物可以有效地用于将醇氧化成醛或酮以及生产内酯。

公开(公告)号：EP0598910A4

公开(公告)日：1994-02-07

申请号：EP93905619

申请日：1993-03-08

申请人： JAPAN TOBACCO INC

发明人： KAWAKAMI HIROSHI JAPAN TOBACCO ,  EBATA TAKASHI JAPAN TOBACCO IN ,  OKANO KOJI JAPAN TOBACCO INC ,  MATSUMOTO KATSUYA JAPAN TOBACC ,  KOSEKI KOSHI JAPAN TOBACCO INC ,  MATSUSHITA HAJIME JAPAN TOBACC

IPC分类号： C07H19/04 ,  C07H23/00 ,  C07D405/04 ,  C07H1/00

CPC分类号： C07H19/04 ,  C07H23/00

摘要： A process for producing a nucleoside derivative (1) by reacting a substituted 2,3-dihydrofuran derivative (2) with an organohalogen compound (3) containing a group 16 element of the periodic table to give a substituted 2-halotetrahydrofuran derivative (4), condensing the derivative (4) with a nucleic acid base to give a substituted nucleoside derivative (5), and reducing the derivative (5), wherein R represents hydrogen, alkyl or R -O-CH2-; R to R represent each hydrogen or a group containing a group 14-17 element of the periodic table; R represents optionally substituted alkyl or phenyl; A represents a group 16 element of the periodic table; B represents a nucleic acid base; and X represents halogen.

公开(公告)号：EP0596108A4

公开(公告)日：1993-01-15

申请号：EP91903826

申请日：1991-02-15

申请人： JAPAN TOBACCO INC

发明人： KUNO HIDEYUKI JAPAN TOBACCO IN ,  SHIBAGAKI MAKOTO JAPAN TOBACCO ,  TAKAHASHI KYOKO JAPAN TOBACCO ,  MATSUSHITA HAJIME JAPAN TOBACC

IPC分类号： B01J21/06 ,  C07C45/29

CPC分类号： B01J21/066 ,  C07C45/29