公开(公告)号：EP1109594B1

公开(公告)日：2004-10-27

申请号：EP99942531.7

申请日：1999-08-30

申请人： Johnson & Johnson Consumer Companies, Inc.

发明人： SUN, Ying ,  OAKESON, Ralph, W. ,  WISNIEWSKI, Stephen, J. ,  WANG, Jonas, C., T. ,  NIEMIEC, Susan, M.

IPC分类号： A61N1/30

CPC分类号： A61M37/0015 ,  A61M2037/0007 ,  A61M2037/0023 ,  A61N1/303

摘要： The present invention relates to an apparatus (100) for transporting a compound through a barrier membrane of a mammal comprising: (a) a vessel (102) having a membrane contacting surface, said surface (104) having a plurality of exposed blades (106) and a channel (108) adjacent to said blades; (b) a reservoir in communication with said channels for storage of said compound; and (c) an electrode in communication with said reservoir, wherein the width of said blades are tapered away from said surface.

公开(公告)号：EP1109594A1

公开(公告)日：2001-06-27

申请号：EP99942531.7

申请日：1999-08-30

申请人： JOHNSON & JOHNSON CONSUMER COMPANIES, INC.

发明人： SUN, Ying ,  OAKESON, Ralph, W. ,  WISNIEWSKI, Stephen, J. ,  WANG, Jonas, C., T. ,  NIEMIEC, Susan, M.

IPC分类号： A61N1/30

CPC分类号： A61M37/0015 ,  A61M2037/0007 ,  A61M2037/0023 ,  A61N1/303

摘要： The present invention relates to an apparatus (100) for transporting a compound through a barrier membrane of a mammal comprising: (a) a vessel (102) having a membrane contacting surface, said surface (104) having a plurality of exposed blades (106) and a channel (108) adjacent to said blades; (b) a reservoir in communication with said channels for storage of said compound; and (c) an electrode in communication with said reservoir, wherein the width of said blades are tapered away from said surface.

公开(公告)号：EP1104280A2

公开(公告)日：2001-06-06

申请号：EP99943639.7

申请日：1999-08-02

申请人： Johnson & Johnson Consumer Companies, Inc.

发明人： NIEMIEC, Susan, M. ,  WANG, Jonas, C., T. ,  WISNIEWSKI, Stephen, J. ,  STENN, Kurt, S. ,  LU, Gwang, Wei

IPC分类号： A61K7/06 ,  A61K7/48 ,  A61K47/10 ,  A61K47/14 ,  A61K47/44 ,  A61P17/14 ,  A61P17/10 ,  A61K47/34

CPC分类号： A61Q19/10 ,  A61K8/0291 ,  A61K8/19 ,  A61K8/34 ,  A61K8/345 ,  A61K8/355 ,  A61K8/365 ,  A61K8/368 ,  A61K8/37 ,  A61K8/375 ,  A61K8/42 ,  A61K8/49 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/602 ,  A61K8/63 ,  A61K8/671 ,  A61K8/678 ,  A61K8/731 ,  A61K8/86 ,  A61K8/90 ,  A61K8/92 ,  A61Q5/006 ,  A61Q7/00 ,  A61Q7/02 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  Y10S514/946 ,  Y10S514/947

摘要： This invention relates to a method for enhancing the transmembrane penetration of benefit agents using a certain non-ionic lipid/surfactant-containing formulation as an enhancing agent, and the compositions used therein. Various active agents, such as anti-dandruff agents, hair growth agents, hair inhibitor agents, anti-acne agents, anti-aging agents, depilatory agents, and depigmentation agents, may be effectively delivered into the skin, hair follicles and sebaceous glands using the compositions of the present invention.