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公开(公告)号：EP1194092B1
公开(公告)日：2007-03-14
申请号：EP00945252.5
申请日：2000-07-07
IPC分类号： A61F7/02
CPC分类号： A61F7/034 , A61B2018/064 , A61F2007/0001 , A61F2007/0276 , A61F2013/00902
摘要： The present invention relates to an exothermic device (500) for topically delivering an active agent comprising a liquid reservoir (220) comprising water, a heating element (210) comprising an oxidizable material, an oxygen-permeable outer-layer (250), an active agent, and a water-impermeable layer (130), wherein upon the rupturing of the liquid reservoir, the water contacts the heating element and the oxygen to create an exothermic reaction.
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公开(公告)号：EP1202691A2
公开(公告)日：2002-05-08
申请号：EP00947098.0
申请日：2000-07-07
CPC分类号： A61F7/034 , A61F2007/0257 , A61F2007/0261 , A61F2007/038 , A61K9/703 , A61K9/7084
摘要： The present invention relates to a multi-layer exothermic bandage comprising an oxygen-impermeable layer, a water-impermeable layer, a heating element layer comprising an oxidizable material, and an active agent layer; and the use thereof.
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公开(公告)号：EP1171195B1
公开(公告)日：2005-03-16
申请号：EP00922164.9
申请日：2000-04-13
CPC分类号： A61N1/044 , A61N1/0412 , A61N1/0436 , A61N1/0448 , A61N1/325
摘要： The present invention relates to an apparatus (100) for the delivery of an active agent through a body surface of a mammal comprising: (a) a housing (102) with a delivery orifice through the housing; (b) a reservoir (120) within the housing for containing the active agent where the reservoir is in communication with the delivery orifice; (c) an electrode within the reservoir where the electrode (112) is capable of being in electronic communication with a current supply unit; and (d) a sensor (118) within the reservoir where the sensor is capable of being in electronic communication with the current supply unit; wherein the current supply unit can modify an electric parameter at the electrode based upon feedback from the sensor.
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公开(公告)号：EP1171195A1
公开(公告)日：2002-01-16
申请号：EP00922164.9
申请日：2000-04-13
CPC分类号： A61N1/044 , A61N1/0412 , A61N1/0436 , A61N1/0448 , A61N1/325
摘要： The present invention relates to an apparatus (100) for the delivery of an active agent through a body surface of a mammal comprising: (a) a housing (102) with a delivery orifice through the housing; (b) a reservoir (120) within the housing for containing the active agent where the reservoir is in communication with the delivery orifice; (c) an electrode within the reservoir where the electrode (112) is capable of being in electronic communication with a current supply unit; and (d) a sensor (118) within the reservoir where the sensor is capable of being in electronic communication with the current supply unit; wherein the current supply unit can modify an electric parameter at the electrode based upon feedback from the sensor.
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公开(公告)号：EP1109594B1
公开(公告)日：2004-10-27
申请号：EP99942531.7
申请日：1999-08-30
发明人： SUN, Ying , OAKESON, Ralph, W. , WISNIEWSKI, Stephen, J. , WANG, Jonas, C., T. , NIEMIEC, Susan, M.
IPC分类号： A61N1/30
CPC分类号： A61M37/0015 , A61M2037/0007 , A61M2037/0023 , A61N1/303
摘要： The present invention relates to an apparatus (100) for transporting a compound through a barrier membrane of a mammal comprising: (a) a vessel (102) having a membrane contacting surface, said surface (104) having a plurality of exposed blades (106) and a channel (108) adjacent to said blades; (b) a reservoir in communication with said channels for storage of said compound; and (c) an electrode in communication with said reservoir, wherein the width of said blades are tapered away from said surface.
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公开(公告)号：EP1194092A1
公开(公告)日：2002-04-10
申请号：EP00945252.5
申请日：2000-07-07
IPC分类号： A61F7/02
CPC分类号： A61F7/034 , A61B2018/064 , A61F2007/0001 , A61F2007/0276 , A61F2013/00902
摘要： The present invention relates to an exothermic device (500) for topically delivering an active agent comprising a liquid reservoir (220) comprising water, a heating element (210) comprising an oxidizable material, an oxygen-permeable outer-layer (250), an active agent, and a water-impermeable layer (130), wherein upon the rupturing of the liquid reservoir, the water contacts the heating element and the oxygen to create an exothermic reaction.
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公开(公告)号：EP1171194A1
公开(公告)日：2002-01-16
申请号：EP00922160.7
申请日：2000-04-13
CPC分类号： A61N1/044 , A61N1/0436 , A61N1/0448 , A61N1/325
摘要： The present invention relates to an apparatus (100) for the delivery of an active agent through a body surface (e.g., the skin or mucosa) of a mammal comprising: a housing with a delivery orifice (134) through the housing (102); an active agent reservoir (120) within the housing for containing the active agent where the active agent reservoir is in communication with the delivery orifice; a fluid reservoir (110) within the housing for containing a fluid; and a semi-permeable membrane (108) in communication with the active agent reservoir and the fluid reservoir for permitting the movement of fluid between the active agent reservoir and the fluid reservoir and substantially preventing the movement of the active agent between the active agent reservoir and the fluid reservoir.
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公开(公告)号：EP1109594A1
公开(公告)日：2001-06-27
申请号：EP99942531.7
申请日：1999-08-30
发明人： SUN, Ying , OAKESON, Ralph, W. , WISNIEWSKI, Stephen, J. , WANG, Jonas, C., T. , NIEMIEC, Susan, M.
IPC分类号： A61N1/30
CPC分类号： A61M37/0015 , A61M2037/0007 , A61M2037/0023 , A61N1/303
摘要： The present invention relates to an apparatus (100) for transporting a compound through a barrier membrane of a mammal comprising: (a) a vessel (102) having a membrane contacting surface, said surface (104) having a plurality of exposed blades (106) and a channel (108) adjacent to said blades; (b) a reservoir in communication with said channels for storage of said compound; and (c) an electrode in communication with said reservoir, wherein the width of said blades are tapered away from said surface.
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