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    PROCESS FOR MAKING TABLET USING RADIOFREQUENCY AND LOSSY COATED PARTICLES
    1.
    发明公开
    PROCESS FOR MAKING TABLET USING RADIOFREQUENCY AND LOSSY COATED PARTICLES 审中-公开
    用于生产射频和有损包衣颗粒，平板电脑

    公开(公告)号：EP3091966A1

    公开(公告)日：2016-11-16

    申请号：EP15701619.7

    申请日：2015-01-08

    申请人： JOHNSON & JOHNSON CONSUMER INC.

    发明人： SZYMCZAK, Christopher E. ,  DAVE, Vipul ,  MCNALLY, Gerard P. ,  COCHRAN, David B. ,  KOLL, Gregory ,  ULRICH, Stephen

    IPC分类号： A61K9/20 ,  A61K9/50 ,  B01J2/00

    CPC分类号： A61K9/2095 ,  A61K9/2081 ,  A61K9/50 ,  A61K31/137 ,  A61K31/138 ,  A61K31/167 ,  B01J2/006 ,  B01J2/18

    摘要： In one aspect the present invention features process for making a tablet comprising at least one pharmaceutically active agent, said method comprising the step of applying radiofrequency energy to a powder blend to sinter said powder blend into said tablet, wherein said powder blend comprises lossy coated particles and said at least one pharmaceutically active agent, wherein said lossy coated particles comprises a substrate that is at least partially coated with a lossy coating comprising at least one activator, wherein said substrate has a Q value of greater than 100 and said activator has a Q value of less than 75.

    摘要翻译： 在一个方面，本发明的特征工艺用于制备片剂，其包含至少一种药物活性剂，所述方法包括施加射频能量的粉末共混物的步骤中烧结所述粉末共混物加入到所述药片，worin所述粉末混合物包括有损涂布颗粒 和所述至少一种药物活性剂，worin所述有损包衣颗粒包括基板那样至少部分地涂覆有一种有损涂层，其包含至少一种活化剂，worin所述衬底具有大于100的Q值和所述活化剂具有的Q- 小于75英里值。